Mathieu Christian, Gonzalez Alvaro, Garcia Alfonso, Johow Magdalena, Badia Catalina, Jara Cecilia, Nuñez Paula, Neira Victor, Montiel Nestor A, Killian Mary Lea, Brito Barbara P
Servicio Agrícola y Ganadero (SAG), Laboratorio y Estación Cuarentenaria de Lo Aguirre, Santiago, Chile.
Departamento de Medicina Preventiva, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, La Pintana, Santiago, Chile.
Transbound Emerg Dis. 2021 Jan;68(1):2-12. doi: 10.1111/tbed.13166. Epub 2019 Apr 4.
In December 2016, low pathogenic avian influenza (LPAI) caused by an H7N6 subtype was confirmed in a grow-out turkey farm located in Valparaiso Region, Chile. Depopulation of exposed animals, zoning, animal movement control and active surveillance were implemented to contain the outbreak. Two weeks later, a second grow-out turkey farm located 70 km north of the first site was also infected by H7N6 LPAI, which subsequently spilled over to one backyard poultry flock. The virus involved in the outbreak shared a close genetic relationship with Chilean aquatic birds' viruses collected in previous years. The A/turkey/Chile/2017(H7N6) LPAI virus belonged to a native South American lineage. Based on the H7 and most of the internal genes' phylogenies, these viruses were also closely related to the ones that caused a highly pathogenic avian influenza outbreak in Chile in 2002. Results from this study help to understand the regional dynamics of influenza outbreaks, highlighting the importance of local native viruses circulating in the natural reservoir hosts.
2016年12月，智利瓦尔帕莱索地区的一个育成火鸡养殖场确诊发生了由H7N6亚型引起的低致病性禽流感（LPAI）。为控制疫情，对受感染动物进行了扑杀、划定了区域、实施了动物移动控制并开展了主动监测。两周后，位于第一个养殖场以北70公里处的第二个育成火鸡养殖场也感染了H7N6低致病性禽流感，随后疫情蔓延到一个后院家禽群。此次疫情涉及的病毒与前几年在智利采集的水禽病毒具有密切的亲缘关系。A/火鸡/智利/2017（H7N6）低致病性禽流感病毒属于南美本土谱系。基于H7基因和大多数内部基因的系统发育分析，这些病毒也与2002年在智利引发高致病性禽流感疫情的病毒密切相关。这项研究的结果有助于了解流感疫情的区域动态，凸显了自然宿主中本地病毒传播的重要性。
