Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
EuroIntervention. 2019 Jun 12;15(3):e253-e260. doi: 10.4244/EIJ-D-18-01003.
This study sought to demonstrate the incidence, predictors, and management of microcatheter collateral channel (CC) tracking failure in retrograde percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions.
Prospectively collected data from 371 consecutive retrograde CTO-PCI procedures between March 2015 and January 2018 were retrospectively analysed. The incidence of initial microcatheter CC tracking failure was 22.5% in 280 procedures with wire CC tracking success. For septal collaterals, CC grade 0-1 collaterals (odds ratio [OR]: 8.3; p<0.001), channel entry angle <90° (OR: 13.0; p=0.001), channel exit angle <90° (OR: 44.3; p=0.004), and Finecross MG as initial microcatheter (OR: 2.7; p=0.032) were independently related to initial microcatheter CC tracking failure. Meanwhile, the only predictor for epicardial collaterals was CC 1 collaterals (OR: 26.9; p<0.001). Frequently applied solutions included microcatheter switching (61.9%), and microcatheter switching combined with GUIDEZILLA (14.3%) or anchoring balloon technique (6.3%).
Initial microcatheter CC tracking failure was found in nearly one quarter of procedures after wire CC tracking success. Independent angiographic predictors of initial microcatheter CC tracking failure included CC 0-1 collaterals, channel entry angle <90°, and channel exit angle <90° for septal collaterals, and CC 1 collaterals for epicardial collaterals.
本研究旨在探讨慢性完全闭塞(CTO)病变逆行经皮冠状动脉介入治疗(PCI)中微导管侧支通道(CC)跟踪失败的发生率、预测因素和处理方法。
回顾性分析了 2015 年 3 月至 2018 年 1 月期间连续 371 例逆行 CTO-PCI 手术的前瞻性收集数据。在 280 例导丝 CC 跟踪成功的手术中,初始微导管 CC 跟踪失败的发生率为 22.5%。对于间隔侧支,CC 0-1 级侧支(比值比[OR]:8.3;p<0.001)、通道入口角度<90°(OR:13.0;p=0.001)、通道出口角度<90°(OR:44.3;p=0.004)和 Finecross MG 作为初始微导管(OR:2.7;p=0.032)与初始微导管 CC 跟踪失败独立相关。同时,心外膜侧支的唯一预测因素是 CC 1 级侧支(OR:26.9;p<0.001)。常用的解决方案包括微导管更换(61.9%),以及微导管更换联合 GUIDEZILLA(14.3%)或锚定球囊技术(6.3%)。
在导丝 CC 跟踪成功后,近四分之一的手术中出现初始微导管 CC 跟踪失败。初始微导管 CC 跟踪失败的独立血管造影预测因素包括间隔侧支的 CC 0-1 级侧支、通道入口角度<90°和通道出口角度<90°,以及心外膜侧支的 CC 1 级侧支。