State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science & Technology, Tianjin 300457, PR China; Key Laboratory of Industrial Fermentation Microbiology (Ministry of Education), Tianjin University of Science & Technology, Tianjin 300457, PR China.
Tianjin Academy of Environmental Science, Tianjin 300191, PR China.
Int J Biol Macromol. 2019 Jul 1;132:692-700. doi: 10.1016/j.ijbiomac.2019.03.240. Epub 2019 Apr 1.
Bacterial cellulose (BC) has numerous excellent properties but the absence of antibacterial activity restricts its applications in biomedical field. Therefore, in order to introduce the antibacterial characteristics into BC; herein, a facile method for incorporation of ZnO nanoparticles (ZnO-NPs) is presented. BC films were first immersed in zinc nitrate solution, followed by treating with NaOH solution, the BC loaded ZnO nanocomposite films were dried by a sheet former instrument at 80 °C for 20 min. The obtained BC/ZnO nanocomposites were characterized by different techniques. XRD results showed the hexagonal wurtzite structure of ZnO-NPs while FE-SEM results displayed the particle size of ZnO-NPs was ranging from 70 to 100 nm. Thermogravimetric study revealed the thermal stability of nanocomposite films. The nanocomposite exhibited photocatalytic activity and revealed 91% degradation of methyl orange (MO) under UV-irradiation within 2 h. Moreover, the nanocomposites demonstrated significant UV-blocking properties and showed antibacterial activities against tested Gram-positive and Gram-negative bacterial strains. This work provides a simple and novel method for the synthesis of BC/ZnO nanocomposite as a functional biomaterial.
细菌纤维素(BC)具有许多优良的性能,但缺乏抗菌活性限制了其在生物医学领域的应用。因此,为了将抗菌特性引入 BC 中;本文提出了一种将 ZnO 纳米粒子(ZnO-NPs)掺入 BC 的简便方法。BC 薄膜首先浸入硝酸锌溶液中,然后用 NaOH 溶液处理,通过片状形成仪在 80°C 下干燥 20 分钟得到负载 ZnO 的纳米复合薄膜。通过不同的技术对所得的 BC/ZnO 纳米复合材料进行了表征。XRD 结果表明 ZnO-NPs 具有六方纤锌矿结构,而 FE-SEM 结果表明 ZnO-NPs 的粒径在 70 到 100nm 之间。热重研究表明了纳米复合材料的热稳定性。纳米复合材料在 UV 照射下显示出光催化活性,在 2 小时内对甲基橙(MO)的降解率达到 91%。此外,纳米复合材料表现出显著的紫外线阻断性能,并对测试的革兰氏阳性和革兰氏阴性细菌菌株表现出抗菌活性。这项工作为合成具有功能的生物材料的 BC/ZnO 纳米复合材料提供了一种简单而新颖的方法。