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成人轻至中度脊柱畸形的微创手术:对重症监护病房及住院时间的影响

Minimally Invasive Surgery for Mild-to-Moderate Adult Spinal Deformities: Impact on Intensive Care Unit and Hospital Stay.

作者信息

Chou Dean, Mundis Gregory, Wang Michael, Fu Kai-Ming, Shaffrey Christopher, Okonkwo David, Kanter Adam, Eastlack Robert, Nguyen Stacie, Deviren Vedat, Uribe Juan, Fessler Richard, Nunley Pierce, Anand Neel, Park Paul, Mummaneni Praveen

机构信息

Department of Neurosurgery, University of California San Francisco, San Francisco, California, USA.

Department of Orthopedic Surgery, Scripps Clinic Torrey Pines, La Jolla, California, USA.

出版信息

World Neurosurg. 2019 Jul;127:e649-e655. doi: 10.1016/j.wneu.2019.03.237. Epub 2019 Apr 1.

Abstract

OBJECTIVE

To compare circumferential minimally invasive (cMIS) versus open surgeries for mild-to-moderate adult spinal deformity (ASD) with regard to intensive care unit (ICU) and hospital lengths of stay (LOS).

METHODS

A retrospective review of 2 multicenter ASD databases with 426 ASD (sagittal vertical axis <6 cm) surgery patients with 4 or more fusion levels and 2-year follow-up was conducted. ICU stay, LOS, and estimated blood loss (EBL) were compared between open and cMIS surgeries.

RESULTS

Propensity matching resulted in 88 patients (44 cMIS, 44 open). cMIS were older (61 vs. 53 years, P = 0.005). Mean levels fused were 6.5 in cMIS and 7.1 in open (P = 0.368). Preoperative lordosis was higher in open than in cMIS (42.7° vs. 40.9°, P = 0.016), and preoperative visual analog score back pain was greater in open than in cMIS (7 vs. 6.2, P = 0.033). Preoperative and postoperative spinopelvic parameters and coronal Cobb angles were not different. EBL was 534 cc in cMIS and 1211 cc in open (P < 0.001). Transfusions were less in cMIS (27.3% vs. 70.5%, P < 0.001). ICU stay was 0.6 days for cMIS and 1.2 days for open (P = 0.009). Hospital LOS was 7.9 days for cMIS versus 9.6 for open (P = 0.804).

CONCLUSIONS

For patients with mild-to-moderate ASD, cMIS surgery had a significantly lower EBL and shorter ICU stay. Major and minor complication rates were lower in cMIS patients than open patients. Overall LOS was shorter in cMIS patients, but did not reach statistical significance.

摘要

目的

比较环形微创手术(cMIS)与开放性手术治疗轻至中度成人脊柱畸形(ASD)患者的重症监护病房(ICU)住院时间和医院住院时间(LOS)。

方法

对2个多中心ASD数据库进行回顾性分析,纳入426例ASD(矢状垂直轴<6 cm)手术患者,融合节段4个或更多,随访2年。比较开放性手术和cMIS手术的ICU住院时间、LOS和估计失血量(EBL)。

结果

倾向评分匹配后得到88例患者(44例cMIS,44例开放性手术)。cMIS组患者年龄更大(61岁对53岁,P = 0.005)。cMIS组平均融合节段为6.5个,开放性手术组为7.1个(P = 0.368)。开放性手术组术前脊柱前凸高于cMIS组(42.7°对40.9°,P = 0.016),开放性手术组术前视觉模拟评分背痛高于cMIS组(7对6.2,P = 0.033)。术前和术后脊柱骨盆参数及冠状面Cobb角无差异。cMIS组EBL为534 cc,开放性手术组为1211 cc(P < 0.001)。cMIS组输血较少(27.3%对70.5%,P < 0.001)。cMIS组ICU住院时间为0.6天,开放性手术组为1.2天(P = 0.009)。cMIS组医院LOS为7.9天,开放性手术组为9.6天(P = 0.804)。

结论

对于轻至中度ASD患者,cMIS手术的EBL显著更低,ICU住院时间更短。cMIS组患者的主要和次要并发症发生率低于开放性手术组患者。cMIS组患者的总体LOS更短,但未达到统计学意义。

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