Morgan A G, Burden R P
Br Med J (Clin Res Ed). 1986 Oct 11;293(6552):935-7. doi: 10.1136/bmj.293.6552.935.
Experience in the use of continuous ambulatory peritoneal dialysis (CAPD) for the treatment of end stage renal failure in Nottingham was reviewed. During six years 150 patients aged from 11 to 73 received this type of treatment. At three years patient actuarial survival was 69% and CAPD technique survival was 41%. Although CAPD was satisfactory as a first treatment for many patients, its long term use was possible in only a few. Actuarial survival of patients who changed to haemodialysis was 64% at one year after the change, suggesting that unsuccessful CAPD increased the risk of death. Hospital haemodialysis was the only suitable form of treatment for most patients in whom CAPD had been abandoned. British renal units have adopted CAPD to a much greater extent than those in Europe, but care in the selection of patients is necessary to reduce mortality, and many patients may eventually need hospital haemodialysis. Greater numbers of hospital haemodialysis places will probably have to be made available to meet this extra demand.
回顾了诺丁汉使用持续性非卧床腹膜透析(CAPD)治疗终末期肾衰竭的经验。在六年期间,150名年龄在11岁至73岁之间的患者接受了这种治疗。三年时患者的精算生存率为69%,CAPD技术生存率为41%。尽管CAPD对许多患者作为初始治疗是令人满意的,但只有少数患者能够长期使用。改为血液透析的患者在改变治疗后的一年精算生存率为64%,这表明CAPD治疗失败会增加死亡风险。医院血液透析是大多数放弃CAPD治疗的患者唯一合适的治疗方式。英国的肾脏治疗单位比欧洲的单位更多地采用了CAPD,但在患者选择上需要谨慎以降低死亡率,而且许多患者最终可能需要医院血液透析。可能需要提供更多的医院血液透析床位来满足这一额外需求。