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成人坏疽性水痘:一种致命的水痘并发症。

Varicella gangrenosum in adult: a fatal chickenpox complication.

作者信息

Sharma Ashish, Agarwal Samarth, Sharma Anamika, Kumar Manoj

机构信息

Urology, King George's Medical University, Lucknow, Uttar-Pradesh, India.

Intensive Care, All India Institute of Medical Sciences, New Delhi, Delhi, India.

出版信息

BMJ Case Rep. 2019 Apr 4;12(4):e226363. doi: 10.1136/bcr-2018-226363.

Abstract

Varicella gangrenosum is a gangrenous ulceration of varicella lesions involving the skin and soft tissues of the body. The term was coined more than 100 years ago. This occurs due to superimposed bacterial infection. The presentation of primary varicella in adults is more severe with catastrophic systemic complications as compared with children. These complications include necrotising fasciitis, disseminated intravascular coagulation, wet/dry gangrene and death, as was seen in our case. Survival is dependent on early diagnosis and treatment. Adequate antibiotic treatment and particularly early radical surgical debridement should be the cornerstone of management. Less than 10 such cases are reported in the literature.

摘要

坏疽性水痘是水痘病变的坏疽性溃疡,累及身体的皮肤和软组织。这个术语在100多年前就已被创造出来。它是由叠加的细菌感染引起的。与儿童相比,成人原发性水痘的表现更为严重,会出现灾难性的全身并发症。这些并发症包括坏死性筋膜炎、弥散性血管内凝血、湿性/干性坏疽和死亡,就像我们这个病例中所见到的。生存取决于早期诊断和治疗。充分的抗生素治疗,尤其是早期彻底的外科清创术应是治疗的基石。文献中报道的此类病例不到10例。

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本文引用的文献

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