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成人坏疽性水痘:一种致命的水痘并发症。

Varicella gangrenosum in adult: a fatal chickenpox complication.

作者信息

Sharma Ashish, Agarwal Samarth, Sharma Anamika, Kumar Manoj

机构信息

Urology, King George's Medical University, Lucknow, Uttar-Pradesh, India.

Intensive Care, All India Institute of Medical Sciences, New Delhi, Delhi, India.

出版信息

BMJ Case Rep. 2019 Apr 4;12(4):e226363. doi: 10.1136/bcr-2018-226363.

DOI:10.1136/bcr-2018-226363
PMID:30948409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6453516/
Abstract

Varicella gangrenosum is a gangrenous ulceration of varicella lesions involving the skin and soft tissues of the body. The term was coined more than 100 years ago. This occurs due to superimposed bacterial infection. The presentation of primary varicella in adults is more severe with catastrophic systemic complications as compared with children. These complications include necrotising fasciitis, disseminated intravascular coagulation, wet/dry gangrene and death, as was seen in our case. Survival is dependent on early diagnosis and treatment. Adequate antibiotic treatment and particularly early radical surgical debridement should be the cornerstone of management. Less than 10 such cases are reported in the literature.

摘要

坏疽性水痘是水痘病变的坏疽性溃疡,累及身体的皮肤和软组织。这个术语在100多年前就已被创造出来。它是由叠加的细菌感染引起的。与儿童相比,成人原发性水痘的表现更为严重,会出现灾难性的全身并发症。这些并发症包括坏死性筋膜炎、弥散性血管内凝血、湿性/干性坏疽和死亡,就像我们这个病例中所见到的。生存取决于早期诊断和治疗。充分的抗生素治疗,尤其是早期彻底的外科清创术应是治疗的基石。文献中报道的此类病例不到10例。

相似文献

1
Varicella gangrenosum in adult: a fatal chickenpox complication.成人坏疽性水痘:一种致命的水痘并发症。
BMJ Case Rep. 2019 Apr 4;12(4):e226363. doi: 10.1136/bcr-2018-226363.
2
Necrotising soft tissue infections as a complication of chickenpox.
Singapore Med J. 1995 Dec;36(6):656-60.
3
Necrotizing fasciitis secondary to chickenpox infection in children.儿童水痘感染继发坏死性筋膜炎
Can J Surg. 2003 Feb;46(1):9-14.
4
Early diagnosis of post-varicella necrotising fasciitis: A medical and surgical emergency.水痘后坏死性筋膜炎的早期诊断:内科及外科急症
Afr J Paediatr Surg. 2016 Jan-Mar;13(1):44-6. doi: 10.4103/0189-6725.181707.
5
Surgical implications of necrotizing fasciitis in children with chickenpox.水痘患儿坏死性筋膜炎的外科治疗意义
J Pediatr Surg. 1996 Aug;31(8):1138-41. doi: 10.1016/s0022-3468(96)90103-7.
6
[Varicella associated necrotizing fasciitis in a child].
Unfallchirurg. 2004 Apr;107(4):325-7. doi: 10.1007/s00113-004-0759-1.
7
Post-varicella epiglottitis and necrotizing fasciitis.水痘后会厌炎和坏死性筋膜炎。
Pediatrics. 2000 Jan;105(1):e13. doi: 10.1542/peds.105.1.e13.
8
Necrotising fasciitis: a sequelae of varicella zoster infection.坏死性筋膜炎:带状疱疹感染的后遗症。
J Plast Reconstr Aesthet Surg. 2011 Jan;64(1):123-7. doi: 10.1016/j.bjps.2010.03.031. Epub 2010 Jun 8.
9
Necrotizing fasciitis with fatal outcome: a report of two cases.坏死性筋膜炎导致致命后果:两例报告
Forensic Sci Med Pathol. 2011 Sep;7(3):278-82. doi: 10.1007/s12024-010-9211-8. Epub 2010 Dec 19.
10
Case records of Wright State University. Arm disuse during varicella.
Pediatr Emerg Care. 2005 Nov;21(11):792-4. doi: 10.1097/01.pec.0000186437.74462.72.

引用本文的文献

1
Varicella Gangrenosum - A Rare Complication: Case Report.坏疽性水痘——一种罕见的并发症:病例报告
Indian Dermatol Online J. 2024 Oct 7;16(3):488-490. doi: 10.4103/idoj.idoj_17_24. eCollection 2025 May-Jun.
2
Critical Chest Wall Necrotizing Fasciitis Triggered by Herpes Zoster: A Case Report.带状疱疹引发的严重胸壁坏死性筋膜炎:病例报告。
Am J Case Rep. 2024 Sep 15;25:e944186. doi: 10.12659/AJCR.944186.
3
Varicella Zoster Reactivation Manifesting as Serpiginous Peripheral Keratitis and Disciform Keratitis Occurring After Necrotizing Fasciitis in an Immunocompromised Male: A Case Report.一名免疫功能低下男性在坏死性筋膜炎后出现水痘带状疱疹再激活,表现为匐行性周边角膜炎和盘状角膜炎:病例报告
Cureus. 2023 Jun 22;15(6):e40787. doi: 10.7759/cureus.40787. eCollection 2023 Jun.
4
Necrotizing Fasciitis After Herpes Zoster Infection: A Rare Case With Diagnostic Difficulties.带状疱疹感染后坏死性筋膜炎:一例诊断困难的罕见病例
Cureus. 2022 May 7;14(5):e24805. doi: 10.7759/cureus.24805. eCollection 2022 May.

本文引用的文献

1
A case of perineal ecthyma gangrenosum.1例会阴坏疽性臁疮。
Turk Pediatri Ars. 2016 Mar 1;51(1):46-8. doi: 10.5152/TurkPediatriArs.2016.1300. eCollection 2016 Mar.
2
Management of varicella gangrenosa: a life-threatening condition from chickenpox.坏疽性水痘的管理:一种由水痘引起的危及生命的病症。
Case Rep Med. 2014;2014:206152. doi: 10.1155/2014/206152. Epub 2014 Nov 19.
3
Ecthyma gangrenosum in a previously healthy infant.一名既往健康的婴儿发生了坏疽性脓皮病。
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