Ball Timothy N, Vasudevan Anupama, Mi Ko Jong, Assar Manish D, McCullough Peter A, Stoler Robert C
Division of Cardiology, Department of Internal Medicine, Baylor University Medical Center, Baylor Heart and Vascular Institute, and Baylor Jack and Jane Hamilton Heart and Vascular HospitalDallas Texas.
Baylor Scott & White Research InstituteDallas Texas.
Proc (Bayl Univ Med Cent). 2018 Sep 11;31(4):407-413. doi: 10.1080/08998280.2018.1471884. eCollection 2018 Oct.
Transcatheter aortic valve implantation (TAVI) is growing in utilization in the USA, and atrioventricular heart block is a common complication of the procedure. In patients with conduction system changes following TAVI, there are no clear guidelines for permanent pacing, leading to difficult clinical decisions on how long to leave temporary transvenous pacemakers in place. The aim of our study was to determine whether changes in electrocardiogram characteristics could predict the need for permanent pacing. A retrospective analysis was conducted of 209 consecutive TAVI patients seen from January 2012 to December 2015 at Baylor Heart and Vascular Hospital, Dallas. The baseline characteristics were similar between those who received a permanent pacemaker (PPM) within 7 days of the procedure (21.1%) and those who did not (78.9%); of those who did receive a PPM, 79.5% were implanted for complete heart block. The median (range) percentage change in the sum of QRS and PR was significantly higher in those who received a PPM (20.2%) than those who did not (7.1%) ( = 0.004). Using the percentage change in the sum of QRS and PR to predict PPM, the area under the curve was found to be 0.69. The optimal cutpoint was found to be 18.9% (sensitivity = 0.63, specificity = 0.73). Our study suggests that delay in the conduction system immediately following TAVI predicts the need for permanent pacing.
经导管主动脉瓣植入术(TAVI)在美国的应用越来越广泛,房室传导阻滞是该手术常见的并发症。在TAVI术后出现传导系统改变的患者中,对于永久性起搏尚无明确的指导原则,这导致在决定临时经静脉起搏器留置时间方面临床决策困难。我们研究的目的是确定心电图特征的变化是否能够预测永久性起搏的需求。对2012年1月至2015年12月期间在达拉斯贝勒心脏和血管医院连续就诊的209例TAVI患者进行了回顾性分析。在术后7天内接受永久性起搏器(PPM)的患者(21.1%)和未接受PPM的患者(78.9%)之间,基线特征相似;在接受PPM的患者中,79.5%是因完全性心脏传导阻滞而植入。接受PPM的患者QRS波群和PR间期总和的中位数(范围)变化百分比(20.2%)显著高于未接受PPM的患者(7.1%)(P = 0.004)。使用QRS波群和PR间期总和的变化百分比来预测PPM,曲线下面积为0.69。最佳切点为18.9%(敏感性 = 0.63,特异性 = 0.73)。我们的研究表明,TAVI术后立即出现的传导系统延迟可预测永久性起搏的需求。