Smith J A, Linder C W, Jay M S, DuRant R H
Clin Pediatr (Phila). 1986 Nov;25(11):566-8. doi: 10.1177/000992288602501105.
Symptomatic infection with Neisseria gonorrhea (NG) has become a major health problem in the adolescent population. While sexually active adults, who carry Neisseria gonorrhea may serve as a reservoir of infection even when asymptomatic, there are few data documenting the frequency of the asymptomatic carrier state in adolescent males. The purpose of this study was to determine the frequency of NG isolates in a sample of asymptomatic adolescent males (ages 13-18 years). Urethral cultures and gram stains were performed on 249 males (95% black) from a lower socioeconomic background presenting to an adolescent clinic for routine health care. Of the 249 males cultured, 177 were without symptoms or signs of urethritis. NG were isolated from four (2.26%) patients (Z = 2.03, p less than or equal to 0.043). They were also isolated from 65 (90.3%) of the remaining 72 who had either symptoms or signs of urethritis. Although 26% of the patients had documented gonococcal disease, only 8% offered a genitourinary complaint at the time of initial evaluation. Our data indicate a low but statistically significant incidence of NG colonization comparable to that found in adult males in this population of asymptomatic adolescent males.
淋病奈瑟菌（NG）的症状性感染已成为青少年人群中的一个主要健康问题。虽然携带淋病奈瑟菌的性活跃成年人即使无症状也可能成为感染源，但很少有数据记录青少年男性无症状携带者状态的频率。本研究的目的是确定无症状青少年男性（13至18岁）样本中NG分离株的频率。对来自社会经济背景较低的249名男性（95%为黑人）进行了尿道培养和革兰氏染色，这些男性前往青少年诊所进行常规医疗保健。在接受培养的249名男性中，177名没有尿道炎的症状或体征。从4名（2.26%）患者中分离出了NG（Z = 2.03，p≤0.043）。在其余72名有尿道炎症状或体征的患者中，也从65名（90.3%）患者中分离出了NG。虽然26%的患者有记录在案的淋球菌疾病，但在初次评估时只有8%的患者有泌尿生殖系统主诉。我们的数据表明，在这群无症状青少年男性中，NG定植的发生率较低，但具有统计学意义，与成年男性中的发生率相当。
