Dengler R, Wolf W, Schubert M, Struppler A
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1986 Sep;17(3):127-32.
The discharge activity of single motor units (MUs) of the first dorsal interosseus muscle was recorded in slight stationary isometric contractions. Normal subjects and patients with parkinsonism of various degrees were investigated. The purpose was to study disturbances of the discharge pattern in the patients and their potential diagnostic role. Automatic signal recognition and statistical analysis of the interval distribution were used. Most MUs of the patients revealed considerable irregularities of their discharge sequences best marked by the so called "floating standard deviation". All patients, also 2 without tremor, showed a characteristic synchronization of their MU discharges ("broad-peak" type). Since the above changes were also seen in the patients with only slight symptoms, these investigations, if methodically simplified, could be of diagnostic value.
在轻微的静态等长收缩过程中，记录了第一背侧骨间肌单个运动单位（MU）的放电活动。对正常受试者和不同程度帕金森病患者进行了研究。目的是研究患者放电模式的紊乱及其潜在的诊断作用。采用了自动信号识别和间隔分布的统计分析方法。患者的大多数运动单位显示出其放电序列有相当大的不规则性，最明显的表现是所谓的“浮动标准差”。所有患者，包括2例无震颤患者，均表现出其运动单位放电的特征性同步（“宽峰”型）。由于上述变化在仅有轻微症状的患者中也可见，因此这些研究如果在方法上简化，可能具有诊断价值。
