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在现代,单纯三尖瓣手术的治疗效果已经得到改善。

Outcomes of Isolated Tricuspid Valve Surgery Have Improved in the Modern Era.

机构信息

Department of Cardiovascular Research, Baylor Scott & White-The Heart Hospital, Plano, Texas.

Department of Cardiothoracic Surgery, Baylor Scott & White-The Heart Hospital, Plano, Texas.

出版信息

Ann Thorac Surg. 2019 Jul;108(1):11-15. doi: 10.1016/j.athoracsur.2019.03.004. Epub 2019 Apr 2.

DOI:10.1016/j.athoracsur.2019.03.004
PMID:30951698
Abstract

BACKGROUND

Surgery for isolated tricuspid valve (TV) disease remains relatively infrequent because of significant patient comorbidities and poor surgical outcomes. This study reviewed the experience with isolated TV surgery in the current era to determine whether outcomes have improved.

METHODS

From 2007 through 2017, 685 TV operations were performed in a single institution, of which 95 (13.9%) operations were isolated TV surgery. Patients were analyzed for disease origin, risk factors, operative mortality and morbidity, and long-term survival.

RESULTS

A total of 95 patients underwent isolated TV surgery, an average of 9 patients per year increasing from an average of 5 per year to 15 per year during the study period. Surgery was reoperative in 41% (38 of 95) of patients, including 11.6% (11 of 95) with prior coronary artery bypass grafting and 29.4% (28 of 95) with prior valve surgery (9 TV, 11 mitral, 2 aortic, 5 mitral and aortic, and 1 mitral and TV). Repair was performed in 71.6% (68 of 95) of patients, and replacement was performed in 28.4% (27 of 95). Operative mortality was 3.2% (3 of 95), with no mortality in the most recent 73 patients over the last 6 years. Stroke occurred in 2.1% (2 of 95) of patients, acute kidney injury requiring dialysis in 5.3% (5 of 95), and the need for new permanent pacemaker in 16.8% (16 of 95).

CONCLUSIONS

In the current era with careful patient selection and periprocedural management, isolated TV surgery can be performed with lower morbidity and mortality than has traditionally been reported with good long-term survival. These outcomes can also serve as a benchmark for catheter-based TV intervention outcomes.

摘要

背景

由于患者合并症多且手术效果不佳,孤立性三尖瓣(TV)疾病的手术治疗仍然相对少见。本研究回顾了当前时代孤立性 TV 手术的经验,以确定手术效果是否有所改善。

方法

2007 年至 2017 年,在一家医院共进行了 685 例 TV 手术,其中 95 例(13.9%)为孤立性 TV 手术。分析患者的疾病来源、危险因素、手术死亡率和发病率以及长期生存率。

结果

共有 95 例患者接受了孤立性 TV 手术,平均每年 9 例,在研究期间,手术量从平均每年 5 例增加到 15 例。41%(38/95)的患者为再次手术,其中 11.6%(11/95)有既往冠状动脉旁路移植术病史,29.4%(28/95)有既往瓣膜手术史(9 例 TV、11 例二尖瓣、2 例主动脉瓣、5 例二尖瓣和主动脉瓣、1 例二尖瓣和 TV)。71.6%(68/95)的患者行修复术,28.4%(27/95)行置换术。手术死亡率为 3.2%(3/95),最近 6 年的最后 73 例患者无死亡。2.1%(2/95)的患者发生脑卒中,5.3%(5/95)发生急性肾损伤需要透析,16.8%(16/95)需要植入新的永久性起搏器。

结论

在当前时代,通过仔细的患者选择和围手术期管理,孤立性 TV 手术可以在降低发病率和死亡率的情况下进行,且长期生存率优于传统报道。这些结果也可以作为经导管 TV 介入治疗结果的基准。

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