Department of Radiology, Ospedali Riuniti, Ancona, Italy.
Department of Radiology, Azienda Ospedaliero Universitaria Ferrara, Ospedale Sant' Anna Cona, Ferrara, Italy.
J Neuroradiol. 2020 Sep;47(5):386-392. doi: 10.1016/j.neurad.2019.03.003. Epub 2019 Apr 2.
Fungal endocarditis is a rare clinical form of infective endocarditis. The main etiology of FE is Candida albicans but also Candida parapsilosis and the overall mortality is high. We report a case of an acute ischemic stroke treated by mechanical thrombectomy, with the histopathological analysis of the retrieved clot followed by the confirmation of fungal endocarditis. An extensive review of the literature has been proposed and three key points concerning the fungal endocarditis predisposing factors, the relation between thrombolysis and hemorrhagic risk and, finally, the importance of clot analysis have been discussed.
真菌性心内膜炎是一种罕见的感染性心内膜炎临床形式。FE 的主要病因是白色念珠菌，但也有近平滑念珠菌，总体死亡率较高。我们报告了一例经机械血栓切除术治疗的急性缺血性脑卒中病例，对取回的血栓进行了组织病理学分析，随后证实为真菌性心内膜炎。我们提出了对文献的广泛回顾，并讨论了三个关键点，即真菌性心内膜炎的易患因素、溶栓与出血风险的关系，以及最后血栓分析的重要性。
