Department of Neurology, Division of Neuro-Epidemiology, New York University School of Medicine, New York, NY 10016, USA; School of Public Health, City University of New York, New York, NY, USA.
Neurol Clin. 2019 May;37(2):171-200. doi: 10.1016/j.ncl.2019.01.005.
The systemic vasculitides are heterogeneous clinicopathologic disorders that share the common feature of vascular inflammation. The resulting disorder can vary depending on involvement of specific organs, caliber of blood vessels, the underlying inflammatory process, and individual host factors. The cumulative result is diminished blood flow, vascular alterations, and eventual occlusion with variable ischemia, necrosis, and tissue damage. An international revised nomenclature system provides the necessary nosology and findings relevant to classify each of the vasculitides. This article is an introduction and overview of the clinical presentation, differential diagnosis, laboratory evaluation, and treatment of systemic and nervous system vasculitides.
系统性血管炎是一组异质性的临床病理疾病，具有血管炎症的共同特征。其临床表现因受累的特定器官、血管口径、潜在炎症过程和个体宿主因素而异。其结果是血流减少、血管改变，最终出现不同程度的缺血、坏死和组织损伤。国际修订的命名系统提供了必要的分类学和发现，有助于对每种血管炎进行分类。本文是对系统性和神经系统血管炎的临床表现、鉴别诊断、实验室评估和治疗的介绍和概述。
