二级医疗保健中患银屑病的儿童：临床特征及共病情况与普遍发表的数据存在差异

[Children with psoriasis in secondary care: Clinical aspects and comorbidities diverge from the generally published data].

作者信息

Mahé E, Maccari F, Ruer-Mulard M, Bodak N, Barthelemy H, Nicolas C, Pépin E, Pillette-Delarue M, Buzenet C, Delaire P-L, Nadaud M, Bouscarat F, Drouot-Lhoumeau D, Lepelley-Dupont C, Acher A, Beauchet A, Corgibet F

机构信息

Service de dermatologie, hôpital Victor-Dupouy, 69, rue du Lieutenant-Colonel Prud'hon, 95100 Argenteuil, France.

Cabinet libéral, 94210 La Varenne-Saint-Hilaire, France.

出版信息

Ann Dermatol Venereol. 2019 May;146(5):354-362. doi: 10.1016/j.annder.2019.01.024. Epub 2019 Apr 4.

DOI:10.1016/j.annder.2019.01.024

PMID:30954294

Abstract

BACKGROUND

Psoriasis affects 0.2-0.7 % of children and is associated with obesity. Published studies have been conducted in hospital settings (tertiary care). The PsoLib study evaluated childhood psoriasis in private practice (secondary care) in terms of epidemiology, clinical aspects and comorbidities.

PATIENTS AND METHODS

This was a non-interventional, cross-sectional, multicenter study of children with psoriasis performed by 41 dermatologists working in private practice. The clinical and therapeutic aspects and comorbidities were systemically evaluated. We compared data to the χ-Psocar study performed in hospitals using the same methodology.

RESULTS

In all, 207 children (girls: 60.4 %; mean age: 10.5±4.2 years) were included. Scalp psoriasis (40.6 %) was the most frequent clinical type, while plaque psoriasis represented 26 % of cases. Nail, tongue, and arthritic involvement were rare. Less than 1 % of children suffered from hypertension, diabetes or dyslipidemia, but 16.4 % were overweight and 7.0 % were obese. Severity (PG≥4 at peak) was associated with excess weight (P=0.01).

CONCLUSION

Scalp psoriasis is the most frequent clinical type of psoriasis in childhood. Comorbidities and extracutaneous localization are rare. Even in private practice, the severity of the disease is associated with excess weight.

摘要

背景

银屑病影响0.2%-0.7%的儿童，且与肥胖相关。已发表的研究是在医院环境（三级医疗）中进行的。PsoLib研究从流行病学、临床方面和合并症角度评估了私人诊所（二级医疗）中的儿童银屑病情况。

患者与方法

这是一项由41名私人执业皮肤科医生开展的关于儿童银屑病的非干预性横断面多中心研究。对临床、治疗方面及合并症进行了系统评估。我们将数据与采用相同方法在医院进行的χ-Psocar研究的数据进行了比较。

结果

共纳入207名儿童（女孩：60.4%；平均年龄：10.5±4.2岁）。头皮银屑病（40.6%）是最常见的临床类型，而斑块状银屑病占病例的26%。指甲、舌头和关节受累情况少见。不到1%的儿童患有高血压、糖尿病或血脂异常，但16.4%超重，7.0%肥胖。病情严重程度（峰值时PG≥4）与体重超标相关（P=0.01）。