Department of Biomedical Engineering, University of Strathclyde, Glasgow, G4 0NS, UK.
Department of Biomedical Engineering, University of Strathclyde, Glasgow, G4 0NS, UK.
Biosens Bioelectron. 2019 Jun 1;134:57-67. doi: 10.1016/j.bios.2019.03.055. Epub 2019 Mar 29.
This review article presents an overview of recent work on electrochemical biosensors developed using microfabrication processes, particularly sensors used to achieve sensitive and specific detection of DNA sequences. Such devices are important as they lend themselves to miniaturisation, reproducible mass-manufacture, and integration with other previously existing technologies and production methods. The review describes the current state of these biosensors, novel methods used to produce them or enhance their sensing properties, and pathways to deployment of a complete point-of-care biosensing system in a clinical setting.
这篇综述文章介绍了使用微制造工艺开发的电化学生物传感器的最新研究工作概述，特别是用于实现 DNA 序列灵敏和特异性检测的传感器。这些设备非常重要，因为它们易于小型化、可重复的大规模制造，并且可以与其他先前存在的技术和生产方法集成。该综述描述了这些生物传感器的现状、用于生产它们或增强其传感性能的新方法，以及在临床环境中部署完整的即时检测生物传感系统的途径。
