Departments of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo Chuo-ku, Kumamoto, 860-8556, Japan.
Department of Neurosurgery, Saiseikai Kumamoto Hospital, Kumamoto, Japan.
Acta Neurochir (Wien). 2019 Jun;161(6):1191-1195. doi: 10.1007/s00701-019-03840-5. Epub 2019 Apr 6.
Radiation therapy is associated with the subsequent development of cerebral aneurysms; however, stereotactic radiosurgery (SRS)-associated aneurysm cases have not been well documented, with only 18 cases reported to date. We present a case of intracranial aneurysms with the rupture occurring 20 years after SRS for a growth hormone-producing pituitary adenoma. This is the first report of aneurysms diagnosed following transsphenoidal surgery and SRS for pituitary adenoma. We believe that the aneurysm reported here is a consequence of the SRS treatment, and thus this may be a very rare long-term complication following radiation treatments.
放射治疗后会并发颅内动脉瘤,但目前仅有 18 例相关病例报道,因此立体定向放射外科(SRS)相关的颅内动脉瘤尚未得到充分证实。我们报告了一例 SRS 治疗生长激素型垂体腺瘤 20 年后发生破裂的颅内动脉瘤。这是首例经蝶窦手术和 SRS 治疗垂体瘤后诊断为颅内动脉瘤的病例。我们认为,这里报告的动脉瘤是 SRS 治疗的结果,因此这可能是放射治疗后非常罕见的长期并发症。