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生长激素型垂体腺瘤立体定向放射外科治疗后诊断为颈内动脉动脉瘤:病例报告及文献复习。

Internal carotid artery aneurysms diagnosed after stereotactic radiosurgery for a growth hormone-secreting pituitary adenoma: a case report and literature review.

机构信息

Departments of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo Chuo-ku, Kumamoto, 860-8556, Japan.

Department of Neurosurgery, Saiseikai Kumamoto Hospital, Kumamoto, Japan.

出版信息

Acta Neurochir (Wien). 2019 Jun;161(6):1191-1195. doi: 10.1007/s00701-019-03840-5. Epub 2019 Apr 6.

Abstract

Radiation therapy is associated with the subsequent development of cerebral aneurysms; however, stereotactic radiosurgery (SRS)-associated aneurysm cases have not been well documented, with only 18 cases reported to date. We present a case of intracranial aneurysms with the rupture occurring 20 years after SRS for a growth hormone-producing pituitary adenoma. This is the first report of aneurysms diagnosed following transsphenoidal surgery and SRS for pituitary adenoma. We believe that the aneurysm reported here is a consequence of the SRS treatment, and thus this may be a very rare long-term complication following radiation treatments.

摘要

放射治疗后会并发颅内动脉瘤,但目前仅有 18 例相关病例报道,因此立体定向放射外科(SRS)相关的颅内动脉瘤尚未得到充分证实。我们报告了一例 SRS 治疗生长激素型垂体腺瘤 20 年后发生破裂的颅内动脉瘤。这是首例经蝶窦手术和 SRS 治疗垂体瘤后诊断为颅内动脉瘤的病例。我们认为,这里报告的动脉瘤是 SRS 治疗的结果,因此这可能是放射治疗后非常罕见的长期并发症。

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