Grendas Leandro N, Rojas Sasha M, Rodante Demián E, Puppo Soledad, Vidjen Patricia, Portela Alicia, Daray Federico M
Institute of Pharmacology, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
"Dr. Teodoro Álvarez" General Hospital. Dr. Juan Felipe Aranguren 2701, Buenos Aires, Argentina.
Arch Suicide Res. 2020;24(sup2):S251-S263. doi: 10.1080/13811118.2019.1592040. Epub 2019 May 7.
The current study aimed to compare suicide-related variables as a function of 1) family history of suicidal behavior and 2) child sexual abuse among patients hospitalized for a suicide attempt or active suicidal ideation. Family history of suicidal behavior and child sexual abuse were examined independently and in combination as a diathesis for a high-risk suicidal phenotype. A multicenter cross-sectional study was designed to compare data obtained from 292 patients hospitalized for suicidal behavior. Demographic and clinical variables were compared among Group 1 (patients who reported both family history of suicidal behavior and child sexual abuse), Group 2 (patients who reported only family history of suicidal behavior), Group 3 (patients who reported only child sexual abuse), and Group 4 (patients who did not report family history of suicidal behavior or childhood sexual abuse). A multinomial logistic regression was used to examine suicide-related variables associated with each group and to compare differences between groups. Group 1 and 3 endorsed a higher number of previous suicide attempts and were more likely to be younger at the first suicide attempt compared to Group 4. Group differences remained after adjustment in a multinomial regression model. The current findings suggest that child sexual abuse may be more strongly related to suicide risk among high risk patients than family history of suicidal behavior.
本研究旨在比较因自杀未遂或有强烈自杀意念而住院的患者中，与自杀相关的变量作为1）自杀行为家族史和2）儿童性虐待的函数关系。分别独立考察了自杀行为家族史和儿童性虐待，并将两者结合起来作为高危自杀表型的素质因素进行研究。一项多中心横断面研究旨在比较从292名因自杀行为住院的患者中获得的数据。在第1组（报告有自杀行为家族史和儿童性虐待的患者）、第2组（仅报告有自杀行为家族史的患者）、第3组（仅报告有儿童性虐待的患者）和第4组（未报告有自杀行为家族史或儿童期性虐待的患者）之间比较人口统计学和临床变量。采用多项逻辑回归分析与每组相关的自杀相关变量，并比较组间差异。与第4组相比，第1组和第3组报告的既往自杀未遂次数更多，首次自杀未遂时的年龄更可能更小。在多项回归模型调整后，组间差异依然存在。目前的研究结果表明，在高危患者中，儿童性虐待可能比自杀行为家族史与自杀风险的关系更为密切。
