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儿童性虐待和自杀行为家族史对高危自杀患者的不同影响

Differential Impact of Child Sexual Abuse and Family History of Suicidal Behavior in High-Risk Suicidal Patients.

作者信息

Grendas Leandro N, Rojas Sasha M, Rodante Demián E, Puppo Soledad, Vidjen Patricia, Portela Alicia, Daray Federico M

机构信息

Institute of Pharmacology, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.

"Dr. Teodoro Álvarez" General Hospital. Dr. Juan Felipe Aranguren 2701, Buenos Aires, Argentina.

出版信息

Arch Suicide Res. 2020;24(sup2):S251-S263. doi: 10.1080/13811118.2019.1592040. Epub 2019 May 7.

Abstract

The current study aimed to compare suicide-related variables as a function of 1) family history of suicidal behavior and 2) child sexual abuse among patients hospitalized for a suicide attempt or active suicidal ideation. Family history of suicidal behavior and child sexual abuse were examined independently and in combination as a diathesis for a high-risk suicidal phenotype. A multicenter cross-sectional study was designed to compare data obtained from 292 patients hospitalized for suicidal behavior. Demographic and clinical variables were compared among Group 1 (patients who reported both family history of suicidal behavior and child sexual abuse), Group 2 (patients who reported only family history of suicidal behavior), Group 3 (patients who reported only child sexual abuse), and Group 4 (patients who did not report family history of suicidal behavior or childhood sexual abuse). A multinomial logistic regression was used to examine suicide-related variables associated with each group and to compare differences between groups. Group 1 and 3 endorsed a higher number of previous suicide attempts and were more likely to be younger at the first suicide attempt compared to Group 4. Group differences remained after adjustment in a multinomial regression model. The current findings suggest that child sexual abuse may be more strongly related to suicide risk among high risk patients than family history of suicidal behavior.

摘要

本研究旨在比较因自杀未遂或有强烈自杀意念而住院的患者中,与自杀相关的变量作为1)自杀行为家族史和2)儿童性虐待的函数关系。分别独立考察了自杀行为家族史和儿童性虐待,并将两者结合起来作为高危自杀表型的素质因素进行研究。一项多中心横断面研究旨在比较从292名因自杀行为住院的患者中获得的数据。在第1组(报告有自杀行为家族史和儿童性虐待的患者)、第2组(仅报告有自杀行为家族史的患者)、第3组(仅报告有儿童性虐待的患者)和第4组(未报告有自杀行为家族史或儿童期性虐待的患者)之间比较人口统计学和临床变量。采用多项逻辑回归分析与每组相关的自杀相关变量,并比较组间差异。与第4组相比,第1组和第3组报告的既往自杀未遂次数更多,首次自杀未遂时的年龄更可能更小。在多项回归模型调整后,组间差异依然存在。目前的研究结果表明,在高危患者中,儿童性虐待可能比自杀行为家族史与自杀风险的关系更为密切。

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