Wilke Benjamin K, Cooper Anna R, Aratani Ashley K, Scarborough Mark T, Gibbs C Parker, Spiguel Andre
Division of Orthopaedic Oncology, University of Florida, Gainesville, FL, USA.
Sarcoma. 2019 Mar 5;2019:1342615. doi: 10.1155/2019/1342615. eCollection 2019.
The Patient Reported Outcomes Measurement Information System (PROMIS) is a tool developed by the National Institutes of Health that allows comparisons across conditions or even the United States (U.S.) general population.
Our purpose was to compare PROMIS outcomes between patients who underwent a planned resection to those who underwent an initial unplanned excision of their sarcoma followed by a definitive oncologic resection. We then compared these groups to the U.S. general population.
Eighty-five patients were included and were divided into those who underwent an initial planned resection (67) and unplanned excision (18). These patients were then further categorized based on the length of follow-up since their last surgery, either early (<12 months) or late (>12 months).
We evaluated seven PROMIS domains and found no differences between patients who underwent planned resection versus those who underwent an initial unplanned excision followed by a wide resection of the previous wound bed. When compared to the U.S. population, both cohorts demonstrated significantly improved scores in several emotional health domains.
Patients who undergo an unplanned excision followed by a definitive oncologic procedure have similar PROMIS scores compared to patients who undergo an initial planned resection.
患者报告结局测量信息系统(PROMIS)是美国国立卫生研究院开发的一种工具,可用于跨疾病甚至与美国普通人群进行比较。
我们的目的是比较接受计划性切除的肉瘤患者与最初接受非计划性切除后再进行确定性肿瘤切除的患者之间的PROMIS结局。然后,我们将这些组与美国普通人群进行比较。
纳入85例患者,分为接受初始计划性切除的患者(67例)和接受非计划性切除的患者(18例)。然后根据自上次手术以来的随访时间长短,将这些患者进一步分为早期(<12个月)或晚期(>12个月)。
我们评估了七个PROMIS领域,发现接受计划性切除的患者与最初接受非计划性切除后再对先前伤口床进行广泛切除的患者之间没有差异。与美国人群相比,两个队列在几个情绪健康领域的得分均有显著提高。
与最初接受计划性切除的患者相比,接受非计划性切除后再进行确定性肿瘤手术的患者的PROMIS评分相似。