氯米芬治疗合并红细胞增多症的性腺功能减退症。
Clomiphene for hypogonadism complicated by polycythemia.
作者信息
Francisco Roshirl, Jaroudi Sarah, Murtaza Ali Mariam, Frost Jill, Chemitiganti Rama, Peiris Alan N
机构信息
Texas Tech University Health Sciences Center School of MedicineLubbock Texas.
Department of Internal Medicine, Texas Tech University Health Sciences Center School of Medicine at Permian BasinTexas.
出版信息
Proc (Bayl Univ Med Cent). 2019 Jan 11;32(1):75-77. doi: 10.1080/08998280.2018.1526570. eCollection 2019 Jan.
Abstract
Male hypogonadism is associated with poor sexual function. Testosterone therapy via the intramuscular route is the preferred treatment but is associated with secondary polycythemia. We report a patient in whom clomiphene citrate improved hypogonadal symptoms and restored normal free testosterone levels. Clomiphene is inexpensive and can be given orally in secondary hypogonadism. Clomiphene citrate is a promising alternative in patients who develop secondary polycythemia with testosterone.
摘要
男性性腺功能减退与性功能不佳有关。经肌肉注射途径进行睾酮治疗是首选治疗方法，但会引发继发性红细胞增多症。我们报告了一例患者，枸橼酸氯米芬改善了性腺功能减退症状并恢复了游离睾酮水平正常。氯米芬价格低廉，可用于继发性性腺功能减退的口服给药。对于因睾酮治疗而发生继发性红细胞增多症的患者，枸橼酸氯米芬是一种有前景的替代药物。
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