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阴茎牵引疗法在佩罗尼氏病治疗中的应用:当前证据与未来前景

The use of penile traction therapy in the management of Peyronie's disease: current evidence and future prospects.

作者信息

Valenzuela Robert, Ziegelmann Matthew, Tokar Sam, Hillelsohn Joel

机构信息

Department of Urology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USA.

Department of Urology, Mayo Clinic, Rochester, MN, USA.

出版信息

Ther Adv Urol. 2019 Mar 29;11:1756287219838139. doi: 10.1177/1756287219838139. eCollection 2019 Jan-Dec.

Abstract

Peyronie's disease is a disorder of abnormal and dysregulated wound healing leading to scar formation in the tunica albuginea of the penis. Penile traction therapy has emerged as an attractive therapeutic option for men with Peyronie's disease in both the acute and chronic phases. Currently, clinical studies are limited by lack of randomization, small cohorts, and lack of patient compliance with therapy. Despite these shortcomings, studies have shown a potential benefit with minimal morbidity. Specifically, penile traction may help to preserve or increase penile length and reduce penile curvature when used as monotherapy or as adjuvant therapy for surgical and intralesional treatments. Further study is necessary to define patient characteristics that are predictive of improved outcomes, determine the duration of treatment needed for clinical effect, and improve patient compliance.

摘要

佩罗尼氏病是一种伤口愈合异常和失调的疾病,会导致阴茎白膜形成瘢痕。阴茎牵引疗法已成为佩罗尼氏病男性患者在急性期和慢性期都颇具吸引力的治疗选择。目前,临床研究受到缺乏随机分组、队列规模小以及患者对治疗依从性差的限制。尽管存在这些缺点,但研究表明其具有潜在益处且发病率极低。具体而言,阴茎牵引作为单一疗法或作为手术及病灶内治疗的辅助疗法使用时,可能有助于保持或增加阴茎长度并减少阴茎弯曲度。有必要进一步研究以确定可预测改善结果的患者特征,确定产生临床效果所需的治疗持续时间,并提高患者依从性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6703/6444402/3975cba4c3b8/10.1177_1756287219838139-fig1.jpg

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