Lee Po-Hsin, Chen Yun-An, Fu Pin-Kuei
Department of Internal Medicine Taichung Veterans General Hospital Taichung Taiwan.
Department of Pathology Taichung Veterans General Hospital Taichung Taiwan.
Respirol Case Rep. 2019 Mar 25;7(5):e0419. doi: 10.1002/rcr2.419. eCollection 2019 Jul.
Angiosarcomas are rare soft-tissue sarcomas of endothelial cell origin and have a poor prognosis. Diffuse alveolar haemorrhage (DAH) is a syndrome characterized by the accumulation of intra-alveolar red blood cells. However, neoplastic diseases are not commonly considered in the differential diagnosis of DAH. We report a case of a 27-year-old female with the diagnosis of primary breast angiosarcoma developing DAH. This raised our concern that angiosarcoma with lung metastasis may present with DAH and should be considered as an important fatal differential diagnosis of DAH.
血管肉瘤是一种罕见的起源于内皮细胞的软组织肉瘤，预后较差。弥漫性肺泡出血（DAH）是一种以肺泡内红细胞积聚为特征的综合征。然而，肿瘤性疾病在DAH的鉴别诊断中并不常被考虑。我们报告一例27岁女性，诊断为原发性乳腺血管肉瘤并发生DAH。这引起了我们的关注，即伴有肺转移的血管肉瘤可能表现为DAH，应被视为DAH重要的致死性鉴别诊断。
