a Department of Psychiatry , UT Southwestern Medical Center , Dallas , TX , USA.
b Department of Clinical Neuropsychology , Barrow Neurological Institute , Phoenix , AZ , USA.
J Clin Exp Neuropsychol. 2019 Aug;41(6):565-575. doi: 10.1080/13803395.2019.1588229. Epub 2019 Apr 8.
In a retrospective chart review, 39 patients referred for a clinical neuropsychological examination were identified as showing either mild cognitive impairment of the amnestic type (MCI-A; = 21) or subjective memory complaints but with normal memory function (SMC; = 18). During the clinical interview, patients and informants were routinely asked to make subjective ratings regarding the patient's cognitive and affective functioning in everyday life. The purpose of this study was to determine whether these two patient groups (and their informants) significantly differed in their subjective reports about level of cognitive and affective difficulties. It was predicted that SMC patients would report higher levels of cognitive and emotional dysfunction than MCI-A patients. It was further predicted that MCI-A patients would underreport cognitive difficulties (compared to informant reports); SMC patients would demonstrate the opposite pattern. Results supported these predictions and suggest that routine assessment of subjective experiences of patients in conjunction with informant ratings may aid clinical diagnosis, particularly when the primary complaint is a decline in memory.
在一项回顾性图表审查中,确定了 39 名因临床神经心理学检查而转介的患者,他们表现出轻度认知障碍的遗忘型(MCI-A;n=21)或有主观记忆抱怨但记忆功能正常(SMC;n=18)。在临床访谈中,常规要求患者及其家属对患者日常生活中的认知和情感功能进行主观评估。本研究的目的是确定这两个患者群体(及其家属)在其认知和情感困难程度的主观报告上是否存在显著差异。研究预测 SMC 患者的认知和情绪功能障碍程度会高于 MCI-A 患者。进一步预测 MCI-A 患者会低估认知困难(与家属报告相比);SMC 患者则会呈现相反的模式。结果支持这些预测,并表明与家属评估相结合对患者主观体验的常规评估可能有助于临床诊断,特别是当主要抱怨是记忆力下降时。