Ng Pui Fai, Lee Ka I, Yang Mo, Fei Bin
Institute of Textiles & Clothing, Hong Kong Polytechnic University, Hong Kong, China.
Department of Biomedical Engineering, Hong Kong Polytechnic University, Hong Kong, China.
Polymers (Basel). 2019 Jan 4;11(1):64. doi: 10.3390/polym11010064.
Flexible gel fibers with high stretchability were synthesized from physically cross-linked agar and covalently cross-linked polyacrylamide networks. Such gel material can withstand the temperature required for thermal curing of polydimethylsiloxane (PDMS), when the water in the gel was partially replaced with ethylene glycol. This gel template supported thermal replica molding of PDMS to produce high quality microchannels. Microchannels with different cross sections and representative 3D structures, including bifurcating junction, helical and weave networks, were smoothly fabricated, based on the versatile manipulation of gel templates. This gel material was confirmed as a flexible and reliable template in fabricating 3D microfluidic channels for potential devices.
通过物理交联的琼脂和共价交联的聚丙烯酰胺网络合成了具有高拉伸性的柔性凝胶纤维。当凝胶中的水部分被乙二醇取代时,这种凝胶材料能够承受聚二甲基硅氧烷(PDMS)热固化所需的温度。这种凝胶模板支持PDMS的热复制成型,以生产高质量的微通道。基于凝胶模板的通用操作,顺利制造出了具有不同横截面和代表性三维结构(包括分叉结、螺旋和编织网络)的微通道。这种凝胶材料被证实是制造用于潜在设备的三维微流体通道的一种灵活且可靠的模板。