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全膝关节置换术中使用骨栓进行髓内封闭以减少失血:一项随机对照试验的荟萃分析

Intramedullary sealing with a bone plug in total knee arthroplasty to reduce blood loss: a meta-analysis of randomized controlled trials.

作者信息

Yuenyongviwat Varah, Tuntarattanapong Pakjai, Iamthanaporn Khanin, Hongnaparak Theerawit, Tangtrakulwanich Boonsin

机构信息

Department of Orthopedics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand.

出版信息

J Orthop Surg Res. 2019 Apr 8;14(1):96. doi: 10.1186/s13018-019-1141-x.

DOI:10.1186/s13018-019-1141-x
PMID:30961640
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6454759/
Abstract

BACKGROUND

An intramedullary guide is an instrument that surgeons use to align the distal femoral cut. The opening may become a channel that drains intramedullary blood to the knee joint after surgery if left open during surgery. The authors aimed to evaluate the effects of an intramedullary bone plug with respect to postoperative blood loss from a meta-analysis.

METHODS

The authors performed a systematic review and meta-analysis to compare a sealed opening using an intramedullary bone plug with no bone plug. PubMed, Ovid, Embase, and Cochrane Library were used to identify all publications before May 2018. All of the included studies were evaluated for bias and heterogeneity.

RESULTS

Six hundred and thirty-six patients from four randomized controlled trials were included in this meta-analysis. The pooled results demonstrated that patients with intramedullary plug had lower rates of blood transfusion and lower level of reduced postoperative hemoglobin than patients in whom the intramedullary canal was not plugged.

DISCUSSION

This meta-analysis demonstrated the benefit of intramedullary sealing with a bone plug in total knee arthroplasty with respect to decreased postoperative blood loss.

摘要

背景

髓内导向器是外科医生用于使股骨远端截骨对齐的器械。如果在手术过程中开口保持开放,术后它可能会成为一条将髓内血液引流至膝关节的通道。作者旨在通过荟萃分析评估髓内骨栓对术后失血的影响。

方法

作者进行了一项系统评价和荟萃分析,以比较使用髓内骨栓封闭开口与不使用骨栓的情况。利用PubMed、Ovid、Embase和Cochrane图书馆检索2018年5月之前的所有出版物。对所有纳入研究进行偏倚和异质性评估。

结果

本荟萃分析纳入了来自四项随机对照试验的636例患者。汇总结果表明,与未封堵髓内通道的患者相比,使用髓内骨栓的患者输血率更低,术后血红蛋白降低水平更低。

讨论

这项荟萃分析表明,在全膝关节置换术中使用骨栓进行髓内封闭对减少术后失血有益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6454759/7ea051a269ff/13018_2019_1141_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6454759/eeb6d574efd3/13018_2019_1141_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6454759/197e306106fb/13018_2019_1141_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6454759/c82fdcd01a04/13018_2019_1141_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6454759/027af0aca8c7/13018_2019_1141_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6454759/7ea051a269ff/13018_2019_1141_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6454759/eeb6d574efd3/13018_2019_1141_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6454759/197e306106fb/13018_2019_1141_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6454759/c82fdcd01a04/13018_2019_1141_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6454759/027af0aca8c7/13018_2019_1141_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6454759/7ea051a269ff/13018_2019_1141_Fig5_HTML.jpg

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Minimizing Blood Loss and Transfusions in Total Knee Arthroplasty.全膝关节置换术中减少失血和输血
J Knee Surg. 2018 Aug;31(7):594-599. doi: 10.1055/s-0038-1648223. Epub 2018 May 4.
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Effects of sealing the intramedullary femoral canal in total knee arthroplasty: A randomized study.全膝关节置换术中封闭股骨髓腔的效果:一项随机研究。
Medicine (Baltimore). 2017 Jul;96(29):e7388. doi: 10.1097/MD.0000000000007388.
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[Sealing of Femoral Tunnel with Autologous Bone Graft Decreases Blood Loss].
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髓内、关节周围注射及关节腔内应用氨甲环酸联合治疗对全膝关节置换术后出血的疗效:一项回顾性病例对照研究。
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Comparison of three methods for sealing of the intramedullary femoral canal during total knee arthroplasty; a randomized controlled trial.三种方法在全膝关节置换术中封闭髓内股骨髓腔的比较:一项随机对照试验。
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Allogeneic Blood Transfusion Is a Significant Risk Factor for Surgical-Site Infection Following Total Hip and Knee Arthroplasty: A Meta-Analysis.同种异体输血是全髋关节和膝关节置换术后手术部位感染的重要危险因素:一项荟萃分析。
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