Jault F, Gandjbakhch I, Pavie A, Levasseur J P, Fournier M M, Fontanel M, Cabrol C
Arch Mal Coeur Vaiss. 1986 Jun;79(7):1062-9.
Between January 1978 and December 1984, 141 cases of acute native valve endocarditis were treated surgically in the Department of Thoracic and Cardiovascular Surgery of the Pitié Hospital. The diagnostic criteria of acute native valve endocarditis were the duration of treatment (antibiotic therapy for less than 40 days), the characteristic operative appearances of the lesions, and the results of anatomo-pathological examination of the excised valves. The infecting organism was not isolated in 35% of cases. The aortic valve was the commonest site of infection (65.2% with a high incidence of abscess of the aortic ring, irrespective of the causal organism. The operative mortality was 5.6%. This depended mainly on the preoperative haemodynamic status of the patient. The duration of antibiotic therapy prior to surgery did not seem to be relevant. The 3 years survival rate was 78%. The secondary reoperation rate was 7%. There was a higher incidence of secondary perivalvular regurgitation in patients who had previously had an abscess of the aortic ring.
1978年1月至1984年12月期间，皮蒂医院胸心血管外科对141例急性原发性瓣膜心内膜炎患者进行了手术治疗。急性原发性瓣膜心内膜炎的诊断标准为治疗时长（抗生素治疗少于40天）、病变的特征性手术表现以及切除瓣膜的解剖病理学检查结果。35%的病例中未分离出感染病原体。主动脉瓣是最常见的感染部位（65.2%），主动脉环脓肿的发生率很高，与致病生物体无关。手术死亡率为5.6%。这主要取决于患者术前的血流动力学状态。术前抗生素治疗的时长似乎并无关联。3年生存率为78%。二次手术率为7%。既往有主动脉环脓肿的患者继发性瓣周反流的发生率更高。
