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[心脏原发性肿瘤。诊断、解剖及治疗方面]

[Primary tumors of the heart. Diagnostic, anatomic and therapeutic aspects].

作者信息

Frieh J P, Ninet J, el Kirat M, Sassolas F, Gressier M, Brulé P, Champsaur G

出版信息

Arch Mal Coeur Vaiss. 1986 Jul;79(8):1188-94.

PMID:3096244
Abstract

Primary cardiac tumours are rare. They are usually benign, the most common ones being left atrial myxomas. The authors report their experience of 16 cardiac tumours operated between 1978 and 1985. The patients were 12 adults and 4 children. The tumours were benign in 14 cases and malignant in 2 cases. Complete (14 cases) or incomplete ablation of the tumour was carried out under cardiopulmonary bypass with an early mortality of 6.25 per cent (1 case) and late mortality of 12.5 per cent (the two malignant tumours). The tumours were identified as myxomas in 11 cases, rhabdomyomas in 2 cases, fibroma in 1 case and malignant sarcomas in 2 cases. The average follow-up period of the 13 survivors is 30 months (range 4 months to 5 years) with excellent clinical and anatomical results. Clinical and paraclinical diagnosis of these tumours does not pose any major problems nowadays because of the reliability of the methods of investigation. However, the nature of the tumour is not always predictable and the operative findings are fundamental, not so much for the treatment which is relatively stereotyped but for the prognosis. Age is not a significant prognostic factor as excellent results may be obtained in the very young and the very old despite a sometimes precarious preoperative clinical condition. The benign or malignant nature of the tumour is the only real factor which affects the prognosis.

摘要

原发性心脏肿瘤较为罕见。它们通常是良性的,最常见的是左心房黏液瘤。作者报告了他们在1978年至1985年间对16例心脏肿瘤进行手术的经验。患者中有12名成人和4名儿童。肿瘤为良性的有14例,恶性的有2例。在体外循环下对肿瘤进行了完整切除(14例)或不完全切除,早期死亡率为6.25%(1例),晚期死亡率为12.5%(2例恶性肿瘤)。肿瘤被确诊为黏液瘤的有11例,横纹肌瘤2例,纤维瘤1例,恶性肉瘤2例。13名幸存者的平均随访期为30个月(范围为4个月至5年),临床和解剖学结果良好。由于检查方法的可靠性,如今这些肿瘤的临床和辅助临床诊断并不存在重大问题。然而,肿瘤的性质并非总是可预测的,手术所见至关重要,这并非主要因为治疗方法相对固定,而是对预后而言。年龄并非重要的预后因素,因为尽管有时术前临床状况不稳定,但非常年轻和非常年长的患者都可能取得优异的结果。肿瘤的良性或恶性性质是唯一真正影响预后的因素。

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