前列腺癌RNA或蛋白质生物标志物的研究现状与进展
Research status and progress of the RNA or protein biomarkers for prostate cancer.
作者信息
Song Chunjiao, Chen Huan, Song Chunyu
机构信息
Medical Research Center, Shaoxing People's Hospital/Shaoxing Hospital, Zhejiang University School of Medicine, Shaoxing, Zhejiang Province, China,
Key Laboratory of Microorganism Technology and Bioinformatics Research of Zhejiang Province, Zhejiang Institute of Microbiology, Hangzhou, Zhejiang, China.
出版信息
Onco Targets Ther. 2019 Mar 22;12:2123-2136. doi: 10.2147/OTT.S194138. eCollection 2019.
Prostate cancer is a kind of male malignancy. Recently, a large number of studies have reported many potential biomarkers for the diagnosis and prognosis of prostate cancer. In this literature review, we have collected a number of potential biomarkers for prostate cancer reported in the last 5 years. Among them, some are undergoing Phase III clinical trials, and others have been approved by the US Food and Drug Administration. However, most are still in the period of basic research. The review will contribute to future research to find the biomarkers to guide clinicians to make personalized treatment decisions for each prostate cancer patient.
前列腺癌是一种男性恶性肿瘤。最近，大量研究报告了许多用于前列腺癌诊断和预后的潜在生物标志物。在这篇文献综述中，我们收集了过去5年报道的一些前列腺癌潜在生物标志物。其中，一些正在进行III期临床试验，其他一些已获得美国食品药品监督管理局的批准。然而，大多数仍处于基础研究阶段。该综述将有助于未来的研究找到生物标志物，以指导临床医生为每位前列腺癌患者做出个性化治疗决策。
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