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手部晚期溃疡性鳞状细胞癌伴局部腋窝淋巴结转移——病例报告及文献综述

Advanced Ulcerated Squamous Cell Carcinoma of the Hand with Locoregional Axillary Lymph Node Metastasis - Case Report and Literature Review.

作者信息

Wollina Uwe, Tempel Sven, Albert Wolfgang, Hansel Gesina, Heinig Birgit

机构信息

Academic Teaching Hospital Dresden, Department of Dermatology and Allergology, Dresden, Germany.

Department of Trauma, Reconstructive, and Hand Surgery, Städtisches Klinikum Dresden, Dresden, Germany.

出版信息

Open Access Maced J Med Sci. 2019 Mar 14;7(5):791-793. doi: 10.3889/oamjms.2019.200. eCollection 2019 Mar 15.

DOI:10.3889/oamjms.2019.200
PMID:30962841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6447345/
Abstract

BACKGROUND

Cutaneous squamous cell carcinoma (SCC) of the hand is the most common soft-tissue malignancy in this particular region. A literature survey suggested a higher rate of metastases in advanced SCC of the hand compared to head-and-neck cutaneous SCC.

CASE REPORT

An 84-year-old man presented with an ulcerated firm tumour on the dorsum of his right hand. A diagnostic biopsy confirmed the diagnosis SCC. Imaging suggested an involvement of the tendons of digits 3 and 4. A diagnostic ultrasound suggested a loco-regional axillary lymph node metastasis. After discussion in the interdisciplinary tumour board, amputation of the affected digits followed by lymph node excision was recommended.

CONCLUSIONS

Advanced SCC of the hand requires interdisciplinary management. Amputation is part of the surgical spectrum in advanced cases.

摘要

背景

手部皮肤鳞状细胞癌(SCC)是该特定区域最常见的软组织恶性肿瘤。文献调查表明,与头颈部皮肤SCC相比,手部晚期SCC的转移率更高。

病例报告

一名84岁男性右手背出现一个溃疡的坚实肿瘤。诊断性活检确诊为SCC。影像学检查提示第3和第4指肌腱受累。诊断性超声提示腋窝局部淋巴结转移。在多学科肿瘤委员会讨论后,建议切除患指并随后切除淋巴结。

结论

手部晚期SCC需要多学科管理。截肢是晚期病例手术治疗的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af34/6447345/78d4df3f0973/OAMJMS-7-791-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af34/6447345/e32a1f9335a7/OAMJMS-7-791-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af34/6447345/09124385a932/OAMJMS-7-791-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af34/6447345/78d4df3f0973/OAMJMS-7-791-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af34/6447345/e32a1f9335a7/OAMJMS-7-791-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af34/6447345/09124385a932/OAMJMS-7-791-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af34/6447345/78d4df3f0973/OAMJMS-7-791-g003.jpg

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本文引用的文献

1
Advanced cutaneous squamous cell carcinoma: A retrospective analysis of patient profiles and treatment patterns-Results of a non-interventional study of the DeCOG.高级别皮肤鳞状细胞癌:一项来自 DeCOG 的回顾性患者特征和治疗模式的非干预性研究结果。
Eur J Cancer. 2018 Jun;96:34-43. doi: 10.1016/j.ejca.2018.01.075. Epub 2018 Apr 14.
2
Tumors of the hand.手部肿瘤
Eur J Orthop Surg Traumatol. 2017 Aug;27(6):747-762. doi: 10.1007/s00590-017-1984-y. Epub 2017 Jun 5.
3
Characteristics, Management Techniques, and Outcomes of the Most Common Soft-Tissue Hand Tumors: A Literature Review and Our Experience.
局部晚期皮肤鳞状细胞癌的当前外科治疗:从患者选择到显微外科组织移植。综述。
Front Oncol. 2021 Dec 7;11:783257. doi: 10.3389/fonc.2021.783257. eCollection 2021.
最常见手部软组织肿瘤的特征、管理技术及结果:文献综述与我们的经验
Ann Plast Surg. 2017 Dec;79(6):558-565. doi: 10.1097/SAP.0000000000001148.
4
Skin cancer of the hand: current concepts.手部皮肤癌:当前概念
J Am Acad Orthop Surg. 2015 May;23(5):307-16. doi: 10.5435/JAAOS-D-14-00040.
5
Cutaneous squamous cell carcinoma in Norway 1963-2011: increasing incidence and stable mortality.1963年至2011年挪威皮肤鳞状细胞癌:发病率上升,死亡率稳定。
Cancer Med. 2015 Mar;4(3):472-80. doi: 10.1002/cam4.404. Epub 2015 Jan 26.
6
Surgical options for malignant skin tumors of the hand.手部恶性皮肤肿瘤的手术选择。
Arch Plast Surg. 2013 May;40(3):238-43. doi: 10.5999/aps.2013.40.3.238. Epub 2013 May 16.
7
Trends of cutaneous squamous cell carcinoma in the Netherlands: increased incidence rates, but stable relative survival and mortality 1989-2008.荷兰皮肤鳞状细胞癌的趋势:发病率上升,但相对生存率和死亡率稳定 1989-2008。
Eur J Cancer. 2012 Sep;48(13):2046-53. doi: 10.1016/j.ejca.2012.01.003. Epub 2012 Feb 16.
8
Skin cancers of the hand: a series of 541 malignancies.手部皮肤癌:541 例恶性肿瘤系列。
Plast Reconstr Surg. 2012 Jun;129(6):1329-1336. doi: 10.1097/PRS.0b013e31824ecc58.
9
Mohs surgery is effective for high-risk cutaneous squamous cell carcinoma.Mohs 手术对于高危皮肤鳞状细胞癌有效。
Dermatol Surg. 2010 Oct;36(10):1544-53. doi: 10.1111/j.1524-4725.2010.01576.x.
10
[Squamous cell carcinoma of the palm: a case report].
Acta Orthop Traumatol Turc. 2007 Aug-Oct;41(4):321-5.