Duy Ton Mai, Dang Luu Vu, Viet Phuong Dao, Van Chi Nguyen, Nguyen Quang Anh, Minh Thong Pham, Dat Anh Nguyen, Lien Nguyen Vu Thai, Nga Vu Thi, Chu Dinh Toi
Emergency Department, Bạch Mai Hospital, Hanoi, Vietnam.
Radiology Center, Bach Mai Hospital, Hanoi, Vietnam.
Open Access Maced J Med Sci. 2019 Mar 14;7(5):801-804. doi: 10.3889/oamjms.2019.187. eCollection 2019 Mar 15.
Thrombectomy is recommended to treat for an acute ischemic stroke (AIS) patient with anterior large vessel occlusion. However, there were neither detailed guidelines nor systematic reviews of acute ischemic stroke patients having multiple times or re-occluded arteries.
In our case report, we struggled a multiple (4-times) AIS patient underwent by one intravenous r-tpA and 3 remaining of endovascular treatment of thrombectomy. Especially, the finding of both pulmonary embolism and cerebral arteries occlusion in this patient made us difficult to decide the appropriate treatment plan. The patient was considered having multiple cardiac thrombi pumping out to the brain and pulmonary vessels even in treatment with NOAC (New Oral Anticoagulant). Our priority, normally, was to recanalize the brain vessels compared to the pulmonary arteries.
In conclusion, based on this noticed case study, we want to share our experiences on the diagnosis of ischemic stroke, the strategy in treatment and prevention with anticoagulant therapy.
对于前循环大血管闭塞的急性缺血性卒中(AIS)患者,推荐进行血栓切除术。然而,对于多次发生动脉闭塞或再发动脉闭塞的急性缺血性卒中患者,既没有详细的指南,也没有系统的综述。
在我们的病例报告中,我们诊治了一名多次(4次)发生AIS的患者,该患者接受了一次静脉注射重组组织型纤溶酶原激活剂(r-tpA)治疗,其余3次为血管内血栓切除术治疗。特别是,该患者同时出现肺栓塞和脑动脉闭塞的情况,这使得我们难以确定合适的治疗方案。即使在使用新型口服抗凝药(NOAC)治疗的情况下,该患者仍被认为有多个心脏血栓脱落至脑和肺血管。通常情况下,与肺动脉相比,我们的首要任务是使脑血管再通。
总之,基于这个值得关注的病例研究,我们希望分享我们在缺血性卒中诊断、治疗策略以及抗凝治疗预防方面的经验。