Suppr超能文献

一些香料草本植物的神经保护作用:文献综述

Neuroprotective potency of some spice herbs, a literature review.

作者信息

Khazdair Mohammad Reza, Anaeigoudari Akbar, Hashemzehi Milad, Mohebbati Reza

机构信息

Neurogenic Inflammation Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran.

Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

J Tradit Complement Med. 2018 Apr 30;9(2):98-105. doi: 10.1016/j.jtcme.2018.01.002. eCollection 2019 Apr.

Abstract

In recent years, growing attention has been given to traditional medicine. In traditional medicine a large number of plants have been used to cure neurodegenerative diseases such as Alzheimers disease (AD) and other memory related disorders. (), () and () were used traditionally for dietary, food additive, spice and various medicinal purposes. The Major components of these herbs are carotenoids, monoterpenes and poly phenol compounds which enhanced the neural functions. These medicinal plants increased anti-oxidant, decreased oxidant levels and inhibited acetylcholinesterase activity in the neural system. Furthermore, neuroprotective of plants occur via reduced pro-inflammatory cytokines such as IL-6, IL-1β, TNF-α and total nitrite generation. Therefore, the effects of the above mentioned medicinal and their active constituents improved neurodegenerative diseases which indicate their therapeutic potential in disorders associated with neuro-inflammation and neurotransmitter deficiency such as AD and depression.

摘要

近年来,传统医学越来越受到关注。在传统医学中,大量植物被用于治疗神经退行性疾病,如阿尔茨海默病(AD)和其他与记忆相关的疾病。()、()和()传统上用于饮食、食品添加剂、香料和各种药用目的。这些草药的主要成分是类胡萝卜素、单萜和多酚化合物,它们增强了神经功能。这些药用植物增加了抗氧化剂,降低了氧化剂水平,并抑制了神经系统中的乙酰胆碱酯酶活性。此外,植物的神经保护作用是通过减少促炎细胞因子如IL-6、IL-1β、TNF-α和总亚硝酸盐的产生来实现的。因此,上述药物及其活性成分的作用改善了神经退行性疾病,这表明它们在与神经炎症和神经递质缺乏相关的疾病如AD和抑郁症中具有治疗潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2998/6435951/9690ac6d92cd/fx1.jpg

相似文献

1
Neuroprotective potency of some spice herbs, a literature review.
J Tradit Complement Med. 2018 Apr 30;9(2):98-105. doi: 10.1016/j.jtcme.2018.01.002. eCollection 2019 Apr.
2
Possible treatment with medicinal herbs and their ingredients of lung disorders induced by sulfur mustard exposures: a review.
Environ Sci Pollut Res Int. 2021 Oct;28(39):54191-54208. doi: 10.1007/s11356-021-15697-2. Epub 2021 Aug 11.
4
A Review on Possible Therapeutic Effect of Nigella sativa and Thymoquinone in Neurodegenerative Diseases.
CNS Neurol Disord Drug Targets. 2018;17(6):412-420. doi: 10.2174/1871527317666180702101455.
6
In-vitro evaluation of selected Egyptian traditional herbal medicines for treatment of Alzheimer disease.
BMC Complement Altern Med. 2013 May 30;13:121. doi: 10.1186/1472-6882-13-121.
8
Native Iranian Medicinal Plants with Anti-Vaginal Infection Properties: A Systematic Review.
Infect Disord Drug Targets. 2022;22(6):e010522204326. doi: 10.2174/1871526522666220501171551.
9
Effects of Lamiaceae family plants and their bioactive ingredients on coronavirus-induced lung inflammation.
Food Sci Nutr. 2023 Dec 27;12(3):1528-1544. doi: 10.1002/fsn3.3903. eCollection 2024 Mar.
10
Medicinal herbs in the treatment of neuropathic pain: a review.
Iran J Basic Med Sci. 2018 Apr;21(4):347-358. doi: 10.22038/IJBMS.2018.24026.6021.

引用本文的文献

2
Editorial: Plant and fungal extracts and metabolites in neurotherapy: exploring their pharmacology and potential clinical uses.
Front Pharmacol. 2025 May 6;16:1602574. doi: 10.3389/fphar.2025.1602574. eCollection 2025.
5
Protective effects of Embelin in Benzo[α]pyrene induced cognitive and memory impairment in experimental model of mice.
Curr Res Neurobiol. 2024 Jan 5;6:100122. doi: 10.1016/j.crneur.2023.100122. eCollection 2024.
6
Brain acetylcholinesterase activity and the protective effect of Gac fruit on scopolamine-induced memory impairment in adult zebrafish.
IBRO Neurosci Rep. 2024 Feb 17;16:368-372. doi: 10.1016/j.ibneur.2024.02.004. eCollection 2024 Jun.
7
Mediterranean Shrub Species as a Source of Biomolecules against Neurodegenerative Diseases.
Molecules. 2023 Dec 16;28(24):8133. doi: 10.3390/molecules28248133.
9
Phytochemistry, quality control and medicinal uses of Saffron (.): an updated review.
J Med Life. 2023 Jun;16(6):822-836. doi: 10.25122/jml-2022-0353.
10
Natural Plant Materials as a Source of Neuroprotective Peptides.
Curr Med Chem. 2024;31(31):5027-5045. doi: 10.2174/0929867331666230703145043.

本文引用的文献

2
Immunomodulatory effect of characterized extract of Zataria multiflora on Th, Th and Th in normal and Th polarization state.
Food Chem Toxicol. 2017 Jan;99:119-127. doi: 10.1016/j.fct.2016.11.019. Epub 2016 Nov 21.
4
1-Methyl-4-propan-2-ylbenzene from Thymus vulgaris Attenuates Cholinergic Dysfunction.
Mol Neurobiol. 2017 Sep;54(7):5468-5481. doi: 10.1007/s12035-016-0083-0. Epub 2016 Sep 6.
8
Study of the effect of extract of Thymus vulgaris on anxiety in male rats.
J Tradit Complement Med. 2015 Aug 1;6(3):257-61. doi: 10.1016/j.jtcme.2015.01.001. eCollection 2016 Jul.
9
Natural Products Screening for the Identification of Selective Monoamine Oxidase-B Inhibitors.
European J Med Plants. 2016 May;15(1). doi: 10.9734/EJMP/2016/26453. Epub 2016 May 27.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验