Animal Health Services, AA Deventer, The Netherlands.
PLoS One. 2019 Apr 9;14(4):e0214584. doi: 10.1371/journal.pone.0214584. eCollection 2019.
Trace elements and potential toxic elements were analyzed in bovine livers submitted for autopsy in the Netherlands during the years 2007 to 2018. The age of each animal was recorded. In total, 1544 livers were analyzed for cadmium, cobalt, chromium, copper, iron, molybdenum, nickel, lead, selenium and zinc. Less than 2% of the liver samples were from veal calves. Young animals had significantly higher concentrations of iron and zinc in their livers compared to animals older than one year, while older animals had significantly higher levels of cadmium and molybdenum in their livers. Animals aged 1 to 2 years had the lowest copper and selenium levels. There was a tendency for lower chromium and nickel levels during the last years of the testing period, while copper showed an increase. Lead intoxication was only seen in the youngest group of cattle, while copper intoxication, defined as a liver copper of more than 1000 mg/kg dry matter, occurred in older animals, mainly in animals of 3 to 4 years old. This trend analysis of trace elements in bovine livers of cattle over time in recent years, and the relation of liver element concentrations with age of the animal, provides insight in the uptake and storage of these elements by cattle in The Netherlands. Possible reasons for observed trends and age-related patterns are discussed.
对 2007 年至 2018 年间在荷兰进行尸检的牛肝脏中的微量元素和潜在有毒元素进行了分析。记录了每只动物的年龄。总共分析了 1544 个肝脏样本，以测定镉、钴、铬、铜、铁、钼、镍、铅、硒和锌的含量。不到 2%的肝脏样本来自小牛肉牛犊。与一岁以上的动物相比，年轻动物的肝脏中铁和锌的浓度明显更高，而年龄较大的动物的肝脏中镉和钼的浓度明显更高。1 至 2 岁的动物铜和硒的含量最低。在检测期的最后几年，铬和镍的含量呈下降趋势，而铜的含量呈上升趋势。只有在最年轻的牛群中才观察到铅中毒，而铜中毒（定义为肝脏内铜含量超过 1000mg/kg 干物质）则发生在年龄较大的动物中，主要是 3 至 4 岁的动物中。本研究对近年来牛肝脏中微量元素的时间趋势进行了分析，并探讨了肝脏元素浓度与动物年龄的关系，为了解荷兰牛对这些元素的吸收和储存提供了新视角。对观察到的趋势和与年龄相关的模式的可能原因进行了讨论。
