睾酮的生物积累与生物降解研究进展。
The Bioaccumulation and Biodegradation of Testosterone by .
机构信息
Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), College of Animal Science and Technology, Southwest University, Chongqing 400715, China.
College of Resources and Environment, Southwest University, Chongqing 400715, China.
出版信息
Int J Environ Res Public Health. 2019 Apr 8;16(7):1253. doi: 10.3390/ijerph16071253.
In the present study, the accumulation and degradation of testosterone by were studied. The results showed that C. has a significant ability to eliminate testosterone by bioaccumulation and biodegradation, and during the 96 h experimental period, the data demonstrated that the accumulation of testosterone followed a sigmoidal accumulation pattern. At the end of the experiment, the bioconcentration percentages of testosterone by C. in the high-concentration group and the low-concentration group were 11.49 ± 2.78% and 40.10 ± 1.98%, respectively, and the biodegradation percentages of testosterone were 69.64 ± 4.33% and 42.48 ± 1.92%, respectively. The rate of biodegradation of testosterone by C. mainly depended on the relative initial concentration of testosterone. When the relative initial concentration of testosterone increases, the degradation may gradually change from zero-order kinetics to second-order kinetics.
在本研究中，研究了 对睾酮的积累和降解作用。结果表明，C. 具有通过生物积累和生物降解显著消除睾酮的能力，在 96 小时的实验期间，数据表明睾酮的积累遵循S 型积累模式。实验结束时，C. 在高浓度组和低浓度组中对睾酮的生物浓缩百分比分别为 11.49±2.78%和 40.10±1.98%，对睾酮的生物降解百分比分别为 69.64±4.33%和 42.48±1.92%。C. 对睾酮的生物降解速率主要取决于睾酮的相对初始浓度。当睾酮的相对初始浓度增加时，降解可能逐渐从零级动力学转变为二级动力学。
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