Kreutzer Johannes, Yagci Yusuf
Department of Chemistry, Istanbul Technical University, Maslak, 34469 Istanbul, Turkey.
Center of Excellence for Advanced Materials Research (CEAMR) and Chemistry Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.
Polymers (Basel). 2017 Dec 29;10(1):35. doi: 10.3390/polym10010035.
A considerable amount of the worldwide industrial production of synthetic polymers is currently based on radical polymerization methods. The steadily increasing demand on high performance plastics and tailored polymers which serve specialized applications is driven by the development of new techniques to enable control of polymerization reactions on a molecular level. Contrary to conventional radical polymerization, reversible-deactivation radical polymerization (RDRP) techniques provide the possibility to prepare polymers with well-defined structures and functionalities. The review provides a comprehensive summary over the development of the three most important RDRP methods, which are nitroxide mediated radical polymerization, atom transfer radical polymerization and reversible addition fragmentation chain transfer polymerization. The focus thereby is set on the newest developments in transition metal free systems, which allow using these techniques for biological or biomedical applications. After each section selected examples from materials synthesis and application to biomedical materials are summarized.
目前，全球相当一部分合成聚合物的工业生产基于自由基聚合方法。对高性能塑料和用于特殊应用的定制聚合物的需求不断增加，这是由能够在分子水平上控制聚合反应的新技术的发展所推动的。与传统自由基聚合相反，可逆失活自由基聚合（RDRP）技术提供了制备具有明确结构和功能的聚合物的可能性。本文综述全面总结了三种最重要的RDRP方法的发展，即氮氧自由基介导的自由基聚合、原子转移自由基聚合和可逆加成-断裂链转移聚合。重点关注无过渡金属体系的最新进展，这使得这些技术可用于生物或生物医学应用。每个部分之后，都会总结从材料合成到生物医学材料应用的选定示例。
