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年轻患者外伤性尿道狭窄的尿道重建术:长期随访结果分析——尿控和性功能质量。

Long-term follow-up of urethral reconstruction for blunt urethral injury at a young age: urinary and sexual quality of life outcomes.

出版信息

J Pediatr Urol. 2019 May;15(3):224.e1-224.e6. doi: 10.1016/j.jpurol.2019.02.013. Epub 2019 Mar 6.

Abstract

INTRODUCTION

Little is known about long-term patient-reported outcomes following surgical repair for pediatric blunt urethral trauma.

OBJECTIVE

The purpose was to evaluate long-term urinary outcomes, sexual function, and quality of life (QOL) of patients who undergo urethroplasty for blunt urethral trauma in childhood.

STUDY DESIGN

After IRB approval, we retrospectively reviewed the records of patients who sustained blunt urethral injury at ≤18 years and underwent urethroplasty at our institution between 1978 and 2013. We then used a web-based survey to assess urinary/sexual/ejaculatory function and overall QOL using validated questionnaires.

RESULTS

Of 68 eligible patients, 15 were able to be contacted (table). Median age of injury, age at urethroplasty, and age at follow-up were 17 (4-18), 17 (5-20), and 19 (13.5-21.5) years, respectively. The stricture was membranoprostatic in eight and bulbar in seven patients, with median length of 2 (1.6-2.6) cm. Excision/primary anastomosis was performed in all but three patients who required a buccal graft. Overall, 80% were 'very satisfied' and 20% were 'satisfied' with surgery. One patient reported a subsequent urethral intervention. On urethral stricture surgery patient-reported outcome measurement, the median bother (0 least, 24 worst) was 10 (8-12.5). The force of urine stream (1 strongest, 4 weakest) was 2 (1.5-2), with no report of urinary incontinence. The median Sexual Health Inventory for Men score (0 worst, 25 perfect) was 24 (22.5-24). The median ejaculatory function score (0 worst, 15 normal) was 14 (13-14.75). Six patients had fathered children and none reported infertility. Three patients reported <30° penile curvature not interfering with sex. Median QOL (0 worse, 10 best) was 8 (7.5-8).

CONCLUSIONS

Urethroplasty after blunt urethral injury in young adult population is associated with a high long-term success rate with a low rate of long-term urinary and sexual consequences in adulthood.

摘要

简介

对于儿童钝性尿道外伤的手术修复后,患者长期的报告结果知之甚少。

目的

本研究旨在评估儿童期接受尿道成形术治疗的钝性尿道外伤患者的长期尿流、性功能和生活质量(QOL)。

研究设计

在获得机构审查委员会批准后,我们回顾性地分析了 1978 年至 2013 年期间在我们机构因钝性尿道损伤而接受尿道成形术的患者记录。然后,我们使用基于网络的调查,使用经过验证的问卷评估尿/性/射精功能和整体 QOL。

结果

在 68 名符合条件的患者中,有 15 名患者能够联系上(表)。损伤时的中位年龄、尿道成形术时的年龄和随访时的年龄分别为 17 岁(4-18 岁)、17 岁(5-20 岁)和 19 岁(13.5-21.5 岁)。8 例为膜部-前列腺部狭窄,7 例为球部狭窄,狭窄长度中位数为 2cm(1.6-2.6cm)。除了 3 例需要颊黏膜移植物的患者外,其余患者均行切除/一期吻合术。总的来说,80%的患者对手术“非常满意”,20%的患者“满意”。1 名患者报告随后接受了尿道干预。在尿道狭窄手术患者报告结果测量中,困扰的中位数(最轻微为 0,最严重为 24)为 10(8-12.5)。尿流强度的中位数(最强为 1,最弱为 4)为 2(1.5-2),无尿失禁报告。男性性功能健康调查的中位数(最差为 0,最好为 25)为 24(22.5-24)。射精功能评分的中位数(最差为 0,正常为 15)为 14(13-14.75)。6 名患者已生育,无不孕报告。3 名患者报告阴茎曲度<30°,不影响性生活。生活质量的中位数(最差为 0,最好为 10)为 8(7.5-8)。

结论

在年轻成年人群中,因钝性尿道外伤而进行尿道成形术与长期成功率高相关,成年后发生长期尿和性功能障碍的发生率低。

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