神经鞘瘤样多形性腺瘤：两例报告并文献复习
Schwannoma-Like Pleomorphic Adenoma: Two Cases and a Review of the Literature.
作者信息
Roth Stephen H, Faquin William C, Gimenez Cecilia, Vadalia Bhumika, Frank Douglas K, Li Jian Yi
机构信息
Division of Oral Pathology, Department of Dental Medicine, Long Island Jewish Medical Center, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, 270-05 76th Ave New, Hyde Park, NY, 11040, USA.
Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
出版信息
Head Neck Pathol. 2020 Mar;14(1):166-172. doi: 10.1007/s12105-019-01036-y. Epub 2019 Apr 9.
Schwannoma-like pleomorphic adenoma is a rare variant of the common benign salivary neoplasm, pleomorphic adenoma. This entity's cytomorphology closely mimics a schwannoma, potentially making a diagnosis of cytologic preparations or of surgical specimens a challenge. To the best of our knowledge, there are only six previous reports of schwannoma-like pleomorphic adenoma with eight total cases in the English language literature prior to the addition of the two cases detailed in this report. Our report includes what we believe to be the first documented case of this entity occurring in the submandibular gland. One of our cases occurred in the submandibular gland of a 90-year-old woman and the other occurred in the left parotid gland of a 40-year-old woman. We also examine the diagnostic considerations used to differentiate these two entities.
神经鞘瘤样多形性腺瘤是常见的良性涎腺肿瘤——多形性腺瘤的一种罕见变体。该实体的细胞形态学与神经鞘瘤极为相似，这可能给细胞学涂片或手术标本的诊断带来挑战。据我们所知，在本报告详细描述的两例之前，英文文献中仅有6篇关于神经鞘瘤样多形性腺瘤的报道，共计8例。我们的报告包括我们认为是该实体发生于下颌下腺的首例记录病例。我们的其中一例发生于一名90岁女性的下颌下腺，另一例发生于一名40岁女性的左腮腺。我们还探讨了用于区分这两种实体的诊断要点。
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