Chen Yufan, Tan Zihui, Shah Shitalkumar S, T Loh Kenny W
Department of Anesthesiology, Singapore General Hospital, Singapore.
Ann Card Anaesth. 2019 Apr-Jun;22(2):169-176. doi: 10.4103/aca.ACA_63_18.
Anesthesia for pulmonary endarterectomy (PEA) has always been one of the challenges of anesthesia. As one of the leading cardiothoracic institutions in Southeast Asia, our hospital has vast interest in this subject. A local multidisciplinary team was deployed to an expert center in the United Kingdom (UK), and the experience was then integrated to the care of our patients. We present a case series of ten patients undergoing anesthesia for PEA, a first for our institution, and discuss techniques as well as potential complications.
Patients with chronic thromboembolic pulmonary hypertension were reviewed by a multidisciplinary team, and those who were suitable for surgical intervention subsequently underwent PEA. A total of ten patients were identified and operated on. The perioperative management and conduction of anesthesia for all patients followed a protocol adapted from the expert center in the UK, with revisions to cater to our Asian population.
In the ten patients operated on, eight of them were successfully extubated on the first postoperative day. Apart from one incident of prolonged ventilator usage due to reperfusion lung injury and pneumonia, there were no major respiratory or hemodynamic complications. Certainly, six of the ten patients developed subdural hemorrhage after the commencement of enoxaparin, although none of them sustained any permanent neurological deficits.
We have demonstrated that with careful planning and a well-outlined protocol, anesthesia for PEA in an Asian population can be achieved with favorable outcomes. Further fine-tuning of the protocol is still required based on local expertise.
肺内膜剥脱术(PEA)的麻醉一直是麻醉领域的挑战之一。作为东南亚领先的心胸外科机构之一,我院对该课题有着浓厚的兴趣。我们派遣了一个本地多学科团队前往英国的一个专家中心,之后将相关经验应用于我们患者的护理中。我们展示了一组十例接受PEA麻醉的患者病例系列,这在我们机构尚属首次,并讨论了相关技术以及潜在并发症。
多学科团队对慢性血栓栓塞性肺动脉高压患者进行了评估,适合手术干预的患者随后接受了PEA手术。共确定了十例患者并进行了手术。所有患者的围手术期管理和麻醉实施均遵循源自英国专家中心的方案,并进行了修订以适应我们的亚洲人群。
在接受手术的十例患者中,八例在术后第一天成功拔管。除了一例因再灌注肺损伤和肺炎导致呼吸机使用时间延长外,没有出现重大呼吸或血流动力学并发症。当然,十例患者中有六例在开始使用依诺肝素后发生了硬膜下出血,尽管他们均未出现任何永久性神经功能缺损。
我们已经证明,通过精心规划和完善的方案,亚洲人群的PEA麻醉可以取得良好的效果。仍需要根据当地专业知识对方案进行进一步微调。