色彩医学显示器校准方法对脑 SPECT 图像判读的影响。

Impact of calibration methods for color medical displays on interpreting brain SPECT images.

机构信息

Department of Quantum Medical Technology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, 920-0942, Japan.

Department of Radiological Technology, Kanazawa University Hospital, Kanazawa, Ishikawa, 920-8641, Japan.

出版信息

Med Phys. 2019 Jun;46(6):2580-2588. doi: 10.1002/mp.13532. Epub 2019 May 2.

DOI:10.1002/mp.13532

PMID:30972760

Abstract

PURPOSE

Color images are visualized on medical monitors that are adjusted by a grayscale standard display function (GSDF) or γ2.2. Although the GSDF is visually displayed as a linear graded grayscale, it does not specify how color medical images should be presented. On the other hand, the usual gamma setting for color images is γ2.2, but it has not been standardized. The color standard display function (CSDF) has recently been proposed as a standardized gamma setting for color medical monitors. However, the influence of various gamma settings on image characteristics should be determined. The present study aimed to identify differences in color-scale characteristics on nuclear medicine images displayed on medical monitors adjusted by CSDF, GSDF, and γ2.2.

METHODS

Transverse normal (n = 1) and abnormal (n = 5) brain perfusion images were generated using a mathematical digital phantom. Transverse phantom and clinical brain images are shown using the clinically applied eight-color scale. Five nuclear medicine experts visually assessed phantom and clinical images using a defect severity scale that ranged from zero (no defect) to four (defect). Receiver operating characteristic curves were created and areas under the curves (AUCs) were analyzed. Defect scores for the clinical study were evaluated in the nine segments on basal ganglia slice, and defect scores were summed for each patient.

RESULTS

The average defect score for color A significantly differed in multiple comparison tests, but not in post hoc tests. The ranges of AUC for CSDF, GSDF, and γ2.2 were 0.86-0.94, 0.82-0.94, and 0.88-0.97, respectively. The AUCs of CSDF in all color scales did not significantly differ from other gamma settings. The summed defect scores of CSDF were similar to those of other gamma settings.

CONCLUSION

Nuclear medicine images were equally valid when adjusted by CSDF even at various gamma settings. Nuclear medicine images can be evaluated equally using any gamma setting. Nonetheless, the color gamma setting for medical monitors should be standardized.

摘要

目的

彩色图像在经过灰度标准显示功能（GSDF）或γ2.2 调整的医学监视器上可视化。尽管 GSDF 在视觉上显示为线性渐变灰度，但它并未指定如何呈现彩色医学图像。另一方面，彩色图像的常用伽马设置为γ2.2，但它尚未标准化。最近提出了彩色标准显示功能（CSDF）作为彩色医学监视器的标准化伽马设置。然而，应该确定各种伽马设置对图像特征的影响。本研究旨在确定 CSDF、GSDF 和γ2.2 调整的医学监视器上显示的核医学图像的色彩标度特征差异。

方法

使用数学数字体模生成横向正常（n=1）和异常（n=5）脑灌注图像。使用临床应用的八色标度显示横向体模和临床图像。五位核医学专家使用缺陷严重程度标度（范围为 0 到 4）对体模和临床图像进行视觉评估。创建了接收器操作特征曲线，并分析了曲线下面积（AUC）。对基底节切片的九个节段进行了临床研究的缺陷评分评估，并对每位患者的缺陷评分进行了求和。

结果

在多重比较测试中，颜色 A 的平均缺陷评分存在显著差异，但在后测测试中没有差异。CSDF、GSDF 和γ2.2 的 AUC 范围分别为 0.86-0.94、0.82-0.94 和 0.88-0.97。所有色彩标度下 CSDF 的 AUC 与其他伽马设置均无显著差异。CSDF 的总和缺陷评分与其他伽马设置相似。