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婴幼儿及儿童先天性心脏病手术后的再入院情况

Readmissions Following Congenital Heart Surgery in Infants and Children.

作者信息

Benavidez Oscar J, He Wei, Lahoud-Rahme Manuella

机构信息

Division of Pediatric-Congenital Cardiology, Department of Pediatric, MassGeneral Hospital for Children, Massachusetts General Hospital, Harvard Medical School, 175 Cambridge Street, Suite 510, Boston, MA, 02114, USA.

出版信息

Pediatr Cardiol. 2019 Jun;40(5):994-1000. doi: 10.1007/s00246-019-02104-4. Epub 2019 Apr 11.

Abstract

Thirty-day readmission after congenital heart surgery (CHS) is an important outcome given the vulnerability of pediatric patients. We hypothesized that readmissions after pediatric CHS are common and identifiable risk factors exist. We obtained State Inpatient Databases for Washington, New York, Florida, and California and selected CHS admissions age < 19 years. The main outcome was readmission defined as non-elective hospitalization < 31 days of discharge from index CHS admission. In multivariable analyses using generalized estimating equations, we examined associations of patient-level characteristics (age, sex, race, household income, insurance status, genetic syndromes, co-morbidities, RACHS-1 surgical risk category and complication) and admission characteristics [weekend admission, urgent/emergent admission, and high resource use (HRU)] with 30-day pediatric readmission after adjusting for case mix. Among 8585 index admissions we identified 967 readmissions (11.3%). Median length of stay for readmissions was 5 days, median total charge of $31,973, and mortality rate 1.8%. Among readmissions, 1.7% underwent another CHS of which 44% were HRU, complication rate 88% and mortality 6.25%. In multivariable analysis, age 1 month-1 year AOR 1.3 p = 0.01; Hispanic ethnicity AOR 1.2 p = 0.03; government-insurance AOR 1.3 p = 0.01; RACHS-1 3 complexity AOR 2.4 p < 0.001; RACHS-1 4 + complexity 2.0 p = 0.001; HRU AOR 1.4 p = 0.02; complications AOR 1.1 p = 0.04; and emergent index admission AOR 2.0 p < 0.001 were risk factors for readmission. Over 11% of pediatric CHS admissions result in an unplanned readmission. Hispanic ethnicity, government insurance, HRU admissions, higher case complexity, complications, and emergent index admission are risk factors for readmission.

摘要

考虑到儿科患者的脆弱性,先天性心脏病手术(CHS)后30天再入院是一项重要的预后指标。我们假设儿科CHS术后再入院情况常见且存在可识别的风险因素。我们获取了华盛顿州、纽约州、佛罗里达州和加利福尼亚州的住院患者数据库,并选择了年龄<19岁的CHS入院病例。主要结局是再入院,定义为非选择性住院,在首次CHS入院出院后<31天。在使用广义估计方程的多变量分析中,我们在调整病例组合后,研究了患者层面特征(年龄、性别、种族、家庭收入、保险状况、遗传综合征、合并症、RACHS-1手术风险类别和并发症)以及入院特征[周末入院、紧急/急诊入院和高资源利用(HRU)]与儿科30天再入院之间的关联。在8585例首次入院病例中,我们识别出967例再入院病例(11.3%)。再入院病例的中位住院时间为5天,中位总费用为31,973美元,死亡率为1.8%。在再入院病例中,1.7%接受了另一次CHS手术,其中44%为高资源利用,并发症发生率为88%,死亡率为6.25%。在多变量分析中,1个月至1岁年龄组调整后比值比(AOR)为1.3,p = 0.01;西班牙裔种族AOR为1.2,p = 0.03;政府保险AOR为1.3,p = 0.01;RACHS-1 3级复杂性AOR为2.4,p<0.001;RACHS-1 4级及以上复杂性AOR为2.0,p = 0.001;高资源利用AOR为1.4,p = 0.02;并发症AOR为1.1,p = 0.04;急诊首次入院AOR为2.0,p<0.001,均为再入院的风险因素。超过11%的儿科CHS入院病例导致计划外再入院。西班牙裔种族、政府保险、高资源利用入院、更高的病例复杂性、并发症和急诊首次入院是再入院的风险因素。

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