黄单胞菌野油菜致病变种中分别与细胞分离和 III 型分泌系统相关的两种溶菌转糖基酶。
Two lytic transglycosylases of Xanthomonas campestris pv. campestris associated with cell separation and type III secretion system, respectively.
机构信息
State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, 100 Daxue Road, Nanning, Guangxi 530004, China.
College of Biotechnology, Guilin Medical University, 109 North 2nd Huancheng Road, Guilin, Guangxi 541004, China.
出版信息
FEMS Microbiol Lett. 2019 Apr 1;366(7). doi: 10.1093/femsle/fnz073.
The lytic transglycosylases (LTs) are important enzymes that degrade peptidoglycan of the bacterial cell wall and affect many biological functions. We present here that XC_0706 and XC_3001 are annotated as the LTs in Xanthomonas campestris pv. campestris. XC_0706 is associated with virulence and plays a pivotal role in cell division. Mutation on XC_3001 reduced hypersensitive response induction and the translocation of type III effector, but did not affect the function of the type II secretion system. Further studies showed that multiple LTs genes contribute to efficiency of the type III secretory system in X. campestris pv. campestris.
溶葡糖苷酶（LTs）是一种重要的酶，可降解细菌细胞壁的肽聚糖并影响许多生物学功能。本研究在野油菜黄单胞菌 pv. 野油菜中鉴定 XC_0706 和 XC_3001 为 LTs。XC_0706 与毒性相关，在细胞分裂中起关键作用。XC_3001 突变后降低了过敏性反应诱导和 III 型效应子的易位，但不影响 II 型分泌系统的功能。进一步研究表明，多个 LTs 基因有助于提高野油菜黄单胞菌 pv. 野油菜中 III 型分泌系统的效率。
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