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[退行性腰椎侧凸后路长节段固定及经椎间孔腰椎椎体间融合术后冠状面失衡的危险因素分析]

[Risk factors analysis of coronal imbalance after posterior long-level fixation and transforaminal lumbar interbody fusion for degenerative lumbar scoliosis].

作者信息

Niu Xiaojian, Yang Sizhen, Zhang Ying, Qiu Hao, Chen Wugui, Zhou Chiyu, Chu Tongwei

机构信息

Department of Orthopedics, Second Affiliated Hospital of Army Medical University, Chongqing, 400037, P.R.China.

Department of Orthopedics, Second Affiliated Hospital of Army Medical University, Chongqing, 400037,

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2019 Apr 15;33(4):430-435. doi: 10.7507/1002-1892.201807149.

Abstract

OBJECTIVE

To explore the risk factors of coronal imbalance after posterior long-level fixation and fusion for degenerative lumbar scoliosis.

METHODS

Retrospectivly analyzed the clinical records of 41 patients with degenerative lumbar scoliosis who had received posterior long-level fixation and fusion with selective transforaminal lumbar interbody fusion (TLIF) accompanied by Ponte osteotomy between August 2011 and July 2016. Patients were divided into imbalance group (group A, 11 cases) and balance group (group B, 30 cases) according to state of coronal imbalance measured at last follow-up. The radiographic parameters at preoperation and last follow-up were measured, and the variance of preoperative and last follow-up parameters were calculated. The radiographic parameters included coronal Cobb angle, coronal balance distance (CBD), apical vertebral translation (AVT), apical vertebral rotation (AVR), Cobb angle of lumbar sacral curve (LSC), and L tilt angle (L TA). Univariate analysis was performed for the factors including gender, age, preoperative T value of bone mineral density, number of instrumented vertebra, upper and lower instrumented vertebra, segments of TLIF, decompression, and Ponte osteotomy, as well as the continuous variables of preoperative imaging parameters with significant difference were converted into two-category variables, obtained the influence factors of postoperative coronal imbalance. Multivariate logistic regression analysis was performed to verify the risk factors from the preliminary screened influence factors and the variance of imaging parameters with significant difference between the two groups.

RESULTS

The follow-up time of groups A and B was (3.76±1.02) years and (3.56±1.03) years respectively, there was no significant difference between the two groups ( =0.547, =0.587). The coronal Cobb angle, AVT, LSC Cobb angle, and L TA in group A were significantly higher than those in group B before operation ( <0.05), and all the imaging parameters in group A were significantly higher than those in group B at last follow-up ( <0.05). There was no significant difference between the two groups in parameters including the variance of coronal Cobb angle, AVT, and LSC Cobb angle before and after operation ( >0.05), and there were significant differences between the two groups in parameters including the variance of CBD, L TA, and AVR ( <0.05). Univariate analysis showed that preoperative L TA was the influencing factor of postoperative coronal imbalance ( <0.05). Multivariate logistic regression analysis showed that preoperative L TA≥15° was an independent risk factor of postoperative coronal imbalance, and variance of pre- and post-operative AVR was a protective factor.

CONCLUSION

Preoperative L TA≥15° is an independent risk factor for coronal imbalance in patients with degenerative lumbar scoliosis after posterior long-level fixation and fusion.

摘要

目的

探讨退行性腰椎侧凸后路长节段固定融合术后冠状面失衡的危险因素。

方法

回顾性分析2011年8月至2016年7月期间41例行后路长节段固定融合术并选择性经椎间孔腰椎椎体间融合术(TLIF)联合Ponte截骨术治疗的退行性腰椎侧凸患者的临床资料。根据末次随访时冠状面失衡状态将患者分为失衡组(A组,11例)和平衡组(B组,30例)。测量术前及末次随访时的影像学参数,并计算术前与末次随访参数的差值。影像学参数包括冠状面Cobb角、冠状面平衡距离(CBD)、顶椎平移(AVT)、顶椎旋转(AVR)、腰骶角(LSC)Cobb角和L倾斜角(L TA)。对性别、年龄、术前骨密度T值、固定椎体数量、上下固定椎体、TLIF节段、减压及Ponte截骨等因素进行单因素分析,将术前有显著差异的影像学参数连续变量转换为二分类变量,得出术后冠状面失衡的影响因素。对初步筛选出的影响因素及两组间有显著差异的影像学参数差值进行多因素logistic回归分析,验证危险因素。

结果

A组和B组随访时间分别为(3.76±1.02)年和(3.56±1.03)年,两组间差异无统计学意义(=0.547,=0.587)。术前A组冠状面Cobb角、AVT、LSC Cobb角和L TA均显著高于B组(<0.05),末次随访时A组所有影像学参数均显著高于B组(<0.05)。两组手术前后冠状面Cobb角、AVT和LSC Cobb角差值等参数差异无统计学意义(>0.05),CBD、L TA和AVR差值等参数两组间差异有统计学意义(<0.05)。单因素分析显示术前L TA是术后冠状面失衡的影响因素(<0.05)。多因素logistic回归分析显示术前L TA≥15°是术后冠状面失衡的独立危险因素,手术前后AVR差值是保护因素。

结论

术前L TA≥15°是退行性腰椎侧凸患者后路长节段固定融合术后冠状面失衡的独立危险因素。

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1
[The disputes in the radiographic measurements of sagittal balance and how to deal with them].[矢状面平衡的影像学测量中的争议及应对方法]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2018 Nov 15;32(11):1365-1370. doi: 10.7507/1002-1892.201808080.
2
[RESEARCH PROGRESS OF SURGICAL SELECTION OF FUSION LEVELS FOR DEGENERATIVE SCOLIOSIS].[退变性脊柱侧凸融合节段手术选择的研究进展]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2016 Aug 8;30(8):1044-1048. doi: 10.7507/1002-1892.20160209.
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Degenerative Lumbar Scoliosis.退行性腰椎侧弯
JBJS Rev. 2015 Apr 7;3(4). doi: 10.2106/JBJS.RVW.N.00061.
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Sagittal balance.矢状面平衡
J Neurosurg Spine. 2014 May;20(5):512; discussion 513-4. doi: 10.3171/2013.10.SPINE13793. Epub 2014 Mar 14.

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