Palla John, Sockrider Marianna M
Pediatr Ann. 2019 Apr 1;48(4):e169-e174. doi: 10.3928/19382359-20190326-02.
Congenital lung malformations (CLM) comprise a spectrum of anatomical anomalies of the lungs and respiratory tree. The prenatal growth pattern of CLMs is unpredictable with larger lesions causing life-threatening complications, such as hydrops fetalis, and smaller lesions remaining asymptomatic and potentially regressing. The most common CLMs are congenital pulmonary adenomatoid malformations, bronchopulmonary sequestrations, congenital lobar emphysema, and bronchogenic cysts. All these lesions have clinically similar presentations when symptomatic, but pathophysiologic differences that must be considered when evaluating and treating. This article reviews the most common CLMs, their pathophysiology, clinical presentation, diagnostic considerations, and current literature on the controversies surrounding CLM management. [Pediatr Ann. 2019;48(4):e169-e174.].
先天性肺发育异常（CLM）包括一系列肺部和呼吸树的解剖学异常。CLM的产前生长模式不可预测，较大的病变会导致危及生命的并发症，如胎儿水肿，而较小的病变则无症状且可能消退。最常见的CLM是先天性肺腺瘤样畸形、支气管肺隔离症、先天性大叶性肺气肿和支气管源性囊肿。所有这些病变在出现症状时临床表现相似，但在评估和治疗时必须考虑其病理生理差异。本文综述了最常见的CLM、其病理生理学、临床表现、诊断要点以及关于CLM管理争议的当前文献。[《儿科年鉴》。2019年；48(4):e169 - e174。]
