1 Department of Precision Machinery & Precision Instrumentation, University of Science and Technology of China, Hefei, China.
2 Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, China.
Ultrason Imaging. 2019 Jul;41(4):191-205. doi: 10.1177/0161734619838456. Epub 2019 Apr 16.
Intravascular ultrasound (IVUS) is an important diagnostic method for coronary disease. The lateral and axial resolutions of IVUS systems under study are typically ~120 and ~30 µm, respectively. The lateral resolution has a lower quality than the axial one and is restricted by the aperture size of transducers. In addition, this resolution is difficult to further improve physically. However, IVUS is inherently suitable for lateral deconvolution because of its circular imaging area. In this paper, magnitude-based deconvolution was demonstrated to be feasible in IVUS imaging to improve the lateral resolution. The deconvolution process was first simulated to determine the highest feasible resolution. Next, the method was applied to a real system to validate the feasibility. The lateral resolution was improved significantly, that is, 2°-separated targets could be discerned using a transducer with 4.2° -6 dB lateral resolution.
血管内超声(IVUS)是冠心病的一种重要诊断方法。研究中的 IVUS 系统的横向和轴向分辨率通常分别约为 120μm 和 30μm。横向分辨率的质量低于轴向分辨率,并且受到换能器孔径尺寸的限制。此外,这种分辨率在物理上很难进一步提高。然而,由于其圆形成像区域,IVUS 非常适合进行横向反卷积。本文证明,基于幅度的反卷积在 IVUS 成像中是可行的,可提高横向分辨率。首先通过模拟反卷积过程来确定最高可行的分辨率。接下来,将该方法应用于真实系统以验证其可行性。横向分辨率得到了显著提高,即使用具有 4.2°-6dB 横向分辨率的换能器可以分辨出相隔 2°的目标。