IEEE J Biomed Health Inform. 2020 Feb;24(2):614-625. doi: 10.1109/JBHI.2019.2910566. Epub 2019 Apr 11.
Respiratory sound is able to differentiate sleep stages and provide a non-contact and cost-effective solution for the diagnosis and treatment monitoring of sleep-related diseases. While most of the existing respiratory sound-based methods focus on a limited number of sleep stages such as sleep/wake and wake/rapid eye movement (REM)/non-REM, it is essential to detect sleep stages at a finer level for sleep quality evaluation. In this paper, we for the first time study a sleep stage detection method aiming at classifying sleep states into four sleep stages: wake, REM, light sleep, and deep sleep from the respiratory sound. In addition to extracting time-domain features, frequency-domain features of respiratory sound, non-linear features of snoring sound are devised to better characterize snoring-related signals of respiratory sound. To effectively fuse the three sets of features, a novel feature fusion technique combining the generalized canonical correlation analysis with the ReliefF algorithm is proposed for discriminative feature selection. Final stage detection is achieved with popular classifiers including decision tree, support vector machines, K-nearest neighbor, and the ensemble classifier. To evaluate our proposed method, we built an in-house dataset, which is comprised of 13 nights of sleep audio data from a sleep laboratory. Experimental results indicate that our proposed method outperforms the existing related ones and is promising for large-scale non-contact sleep monitoring.
呼吸声可用于区分睡眠阶段,并为睡眠相关疾病的诊断和治疗监测提供一种非接触且具有成本效益的解决方案。虽然现有的大多数基于呼吸声的方法主要关注睡眠/觉醒和觉醒/快速眼动 (REM)/非 REM 等有限数量的睡眠阶段,但为了进行睡眠质量评估,有必要更精细地检测睡眠阶段。在本文中,我们首次研究了一种旨在将睡眠状态分类为四个睡眠阶段的睡眠阶段检测方法:觉醒、REM、浅睡和深睡。除了提取时域特征外,我们还设计了呼吸声中打鼾声的频域特征和非线性特征,以更好地描述与打鼾相关的呼吸声信号。为了有效地融合这三组特征,我们提出了一种新颖的特征融合技术,将广义典型相关分析与 ReliefF 算法相结合,用于有鉴别力的特征选择。最终的阶段检测采用了流行的分类器,包括决策树、支持向量机、K-最近邻和集成分类器。为了评估我们提出的方法,我们构建了一个内部数据集,该数据集包含来自睡眠实验室的 13 晚睡眠音频数据。实验结果表明,我们提出的方法优于现有的相关方法,有望用于大规模的非接触式睡眠监测。