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[耳内镜手术治疗242例中耳胆脂瘤患者及术后效果分析]

[Management of 242 patients with middle ear cholesteatoma by otoendoscopic surgery and the postoperative effect analysis].

作者信息

Wu N, Wang Z Y, Yu Y J, Zhang W, Yang Q, Chen S J, Hou Z H

机构信息

Department of Otorhinolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Beijing 100853, China.

Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200011, China.

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Apr 7;54(4):251-256. doi: 10.3760/cma.j.issn.1673-0860.2019.04.003.

Abstract

To summarize and discuss the characteristics of endoscopic approach to manage the middle ear cholesteatoma, and to evaluate the operative safety and outcomes based on the data from the multicenter study. The data of 242 cases diagnosed with the middle ear cholesteatoma and received operation through endoscopic approach between June 2016 and June 2017 in six tertiary hospitals in China were analyzed in this work. There were 130 males and 112 females, with the age ranging from 3 to 72 years old. We evaluated the strategy about how to manage the cholesteatoma, discussed the detailed techniques about how to remove the cholesteatoma and to improve the efficiency under endoscopic visualization. Meanwhile, the recurrence rate and residual rate of cholesteatoma as well as the complications in endoscopic approach were summarized. A total of 158 cases were operated in exclusively endoscopic transcanal approach, 72 cases operated in combined approach, and 12 cases operated majorly under microscope and minorly under endoscope. 219 cases were operated in one stage surgery, 23 cases received second look. In the second look, 3 cases were detected with residual cholesteatomas. Among them, 2 cases were found by MRI-DWI examination after the first-stage operation. With endoscopic examination after operation, 17 cases showed retracted pocket recurrence (7%,17/242). With introduction of endoscope in cholesteatoma, 153 cases were achieved canal wall-up operation (63%, 153/242). The complications in endoscopic approach included chord tympani never injury in 27 cases, skin injury of ear canal in 11 cases, tinnitus in 13 cases, vertigo in 7 cases, external ear canal stenosis in 1 case. Using otoendoscope in cholesteatoma surgery would help keeping the normal structures of middle ear as much as possible, benefit to remove the hiding pathologies, help reducing residual cholesteatoma and lowering the rate of canal wall-down operation as well. This study showed good safety of otoendoscopic cholesteatoma surgery, however, strict evaluation of indication and quite good surgical techniques and skills are necessary for avoiding unexpected complication.

摘要

总结并讨论内镜治疗中耳胆脂瘤的特点,基于多中心研究数据评估手术安全性及疗效。本研究分析了2016年6月至2017年6月期间中国6家三级医院242例经内镜手术治疗的中耳胆脂瘤患者的数据。其中男性130例,女性112例,年龄3至72岁。我们评估了胆脂瘤的处理策略,讨论了在内镜视野下切除胆脂瘤及提高手术效率的详细技术。同时,总结了内镜手术中胆脂瘤的复发率、残留率及并发症情况。单纯经耳道内镜手术158例,联合手术72例,主要在显微镜下、辅助在内镜下手术12例。一期手术219例,二期探查23例。二期探查中发现3例残留胆脂瘤,其中2例在一期手术后经MRI-DWI检查发现。术后内镜检查发现17例出现内陷袋复发(7%,17/242)。随着内镜在胆脂瘤手术中的应用,153例实现了上鼓室开放手术(63%,153/242)。内镜手术并发症包括27例鼓索神经损伤、11例耳道皮肤损伤、13例耳鸣、7例眩晕、1例外耳道狭窄。在胆脂瘤手术中使用耳内镜有助于尽可能保留中耳正常结构,利于清除隐匿性病变,有助于减少残留胆脂瘤并降低下鼓室开放手术率。本研究显示耳内镜下胆脂瘤手术安全性良好,然而,严格评估适应证以及具备相当好的手术技术和技巧对于避免意外并发症是必要的。

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