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基于人群的队列研究:阑尾切除术后患儿的护理提供与并发症风险之间的相关性。

Population-based cohort study of the correlation between provision of care and the risk for complications after appendectomy in children.

机构信息

Department of Pediatric Surgery, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden; Departments of Women's and Children's Health, Stockholm, Sweden.

Department of Pediatric Surgery, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden; Departments of Women's and Children's Health, Stockholm, Sweden.

出版信息

J Pediatr Surg. 2019 Nov;54(11):2279-2284. doi: 10.1016/j.jpedsurg.2019.03.013. Epub 2019 Mar 28.

Abstract

PURPOSE

To investigate the impact of hospital administrative level and caseload of pediatric appendectomies on the morbidity and mortality after appendectomy in a population-based cohort of Swedish children.

METHODS

Population-based cohort study including all Swedish children less than 15 years of age that underwent appendectomy for suspected appendicitis, 1987-2009. Patient characteristics and data on postoperative morbidity and mortality were collected from the Swedish National Patient Register and the Swedish Death Register. Primary endpoints were postoperative morbidity and mortality. Two explanatory variables were investigated: hospital administrative level and hospital annual caseload of pediatric appendectomies. Data were analyzed in regression models adjusting for available confounders.

RESULTS

The cohort comprised 55,591 children. The risk for postoperative complications was reduced in specialized pediatric surgical centers and in high caseload centers, compared to other hospitals. There were only seven postoperative deaths within 90 days of appendectomy.

CONCLUSIONS

We found clinically relevant risk reductions for reoperation and for readmission after appendectomy in specialized pediatric surgical centers. Importantly, the risk for postoperative complications was also reduced with increased hospital caseload, indicating that the merit from centralizing the management of pediatric appendectomies to specialized pediatric surgical centers may also be achieved by increasing hospital caseload of pediatric appendectomies in non-pediatric surgical units.

TYPE OF STUDY

Treatment study.

LEVEL OF EVIDENCE

Level II.

摘要

目的

研究医院行政级别和小儿阑尾切除术的病例量对瑞典儿童基于人群的阑尾切除术后发病率和死亡率的影响。

方法

本研究为基于人群的队列研究,纳入了 1987 年至 2009 年期间瑞典所有因疑似阑尾炎而行阑尾切除术的 15 岁以下儿童患者。从瑞典国家患者登记处和瑞典死亡登记处收集患者特征以及术后发病率和死亡率的数据。主要终点为术后发病率和死亡率。研究了两个解释变量:医院行政级别和医院小儿阑尾切除术的年病例量。通过调整了可能的混杂因素的回归模型进行数据分析。

结果

本研究纳入了 55591 例患儿。与其他医院相比,在专门的小儿外科中心和高病例量中心,术后并发症的风险降低。阑尾切除术后 90 天内仅有 7 例死亡。

结论

我们发现,在专门的小儿外科中心,阑尾切除术后再次手术和再次入院的风险显著降低。重要的是,随着医院病例量的增加,术后并发症的风险也降低了,这表明将小儿阑尾切除术的管理集中到专门的小儿外科中心,也可以通过增加非小儿外科单位的小儿阑尾切除术的医院病例量来实现。

研究类型

治疗研究。

证据等级

II 级。

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