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埃及东北部三角洲的急性弛缓性麻痹:前瞻性收集监测数据的回顾性分析。

Acute flaccid paralysis in North East Delta, Egypt: A retrospective analysis of prospectively collected surveillance data.

机构信息

Gamasa District of Health, Dakahlia Governorate, Egypt.

Department of Public Health and Community Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

出版信息

J Infect Public Health. 2019 Sep-Oct;12(5):714-719. doi: 10.1016/j.jiph.2019.03.016. Epub 2019 Apr 13.

DOI:10.1016/j.jiph.2019.03.016
PMID:30992227
Abstract

BACKGROUND

Effective acute flaccid paralysis (AFP) surveillance is crucial in countries approaching the final phase of polio eradication. Thus this study was conducted to highlight the epidemiological pattern of AFP as a surveillance tool for polio in Egypt.

METHODS

A record-based descriptive study was conducted to include all AFP cases (599) reported in the last 9 years starting from January 2009 to December 2017 in Dakahlia, North East of Delta, Egypt.

RESULTS

The overall non-polio AFP rate in less than 15 years old children was 2.99/100,000 during the study period. The majority of cases (98%) were notified within 7 days from onset of the disease, and investigated within 48 h of reporting. The commonest diagnoses were encephalitis (21.3%), myositis (20.2%), neuropathies (19.2%) and Guillain-Barre syndrome (17.8%) with no recorded cases diagnosed as poliomyelitis. The mean annual vaccination coverage rate was 96.1 ± 1.6.

CONCLUSIONS

AFP surveillance system in Dakahlia, Egypt was effective in meeting the WHO surveillance performance indicators ensuring polio-free status and absence of wild polio virus transmission over the last 9 years in this locality. High routine immunization coverage, maintenance and improvement of current levels of surveillance performance are required for optimum surveillance.

摘要

背景

在接近消灭脊灰最后阶段的国家,有效的急性弛缓性麻痹(AFP)监测至关重要。因此,本研究旨在突出 AFP 作为埃及脊灰监测工具的流行病学模式。

方法

本研究采用基于记录的描述性研究,纳入了 2009 年 1 月至 2017 年 12 月 9 年间在埃及东北部达卡利亚报告的所有 AFP 病例(599 例)。

结果

在研究期间,15 岁以下儿童的总非脊灰 AFP 发病率为 2.99/100,000。大多数病例(98%)在发病后 7 天内报告,在报告后 48 小时内进行调查。最常见的诊断为脑炎(21.3%)、肌炎(20.2%)、神经病(19.2%)和格林-巴利综合征(17.8%),无记录的脊灰病例。平均年疫苗接种覆盖率为 96.1±1.6。

结论

埃及达卡利亚的 AFP 监测系统在过去 9 年中有效地满足了世卫组织监测绩效指标,确保了该地区脊灰无疫区状态和野生脊灰病毒传播的不存在。需要保持和提高当前的监测绩效水平,以实现最佳监测。

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