• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Identification of small non-coding RNAs as sperm quality biomarkers for in vitro fertilization.

作者信息

Hua Minmin, Liu Wei, Chen Ying, Zhang Fengjuan, Xu Beiying, Liu Suying, Chen Guowu, Shi Huijuan, Wu Ligang

机构信息

1NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Pharmacy School, Fudan University, Shanghai, 200032 China.

2State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031 China.

出版信息

Cell Discov. 2019 Apr 9;5:20. doi: 10.1038/s41421-019-0087-9. eCollection 2019.

DOI:10.1038/s41421-019-0087-9
PMID:30992999
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6453904/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fb9/6453904/0a01086249d6/41421_2019_87_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fb9/6453904/0a01086249d6/41421_2019_87_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fb9/6453904/0a01086249d6/41421_2019_87_Fig1_HTML.jpg

相似文献

1
Identification of small non-coding RNAs as sperm quality biomarkers for in vitro fertilization.鉴定小非编码RNA作为体外受精的精子质量生物标志物。
Cell Discov. 2019 Apr 9;5:20. doi: 10.1038/s41421-019-0087-9. eCollection 2019.
2
Sperm and seminal plasma RNAs: what roles do they play beyond fertilization?精子和精浆 RNA：它们在受精之外还扮演什么角色？
Reproduction. 2019 Oct;158(4):R113-R123. doi: 10.1530/REP-18-0639.
3
Sperm-carried RNAs play critical roles in mouse embryonic development.精子携带的RNA在小鼠胚胎发育中发挥着关键作用。
Oncotarget. 2017 Jun 27;8(40):67394-67405. doi: 10.18632/oncotarget.18672. eCollection 2017 Sep 15.
4
[Transgenerational transmission mediated by small non-coding RNA in sperm].精子中小非编码RNA介导的跨代传递
Zhonghua Nan Ke Xue. 2016 Nov;22(11):1021-1024.
5
A history of why fathers' RNA matters.父亲的 RNA 为何重要的历史
Biol Reprod. 2018 Jul 1;99(1):147-159. doi: 10.1093/biolre/ioy007.
6
Sperm-borne miRNAs and endo-siRNAs are important for fertilization and preimplantation embryonic development.精子携带的微小RNA和内源性小干扰RNA对受精和植入前胚胎发育很重要。
Development. 2016 Feb 15;143(4):635-47. doi: 10.1242/dev.131755. Epub 2015 Dec 30.
7
Circulating small non-coding RNAs provide new insights into vitamin K nutrition and reproductive physiology in teleost fish.循环中的小非编码 RNA 为研究甲壳动物的维生素 K 营养和生殖生理学提供了新的见解。
Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):39-51. doi: 10.1016/j.bbagen.2018.09.017. Epub 2018 Sep 27.
8
Paternal Contributions to Offspring Health: Role of Sperm Small RNAs in Intergenerational Transmission of Epigenetic Information.父方对后代健康的贡献：精子小RNA在表观遗传信息代际传递中的作用
Front Cell Dev Biol. 2019 Oct 9;7:215. doi: 10.3389/fcell.2019.00215. eCollection 2019.
9
Non-coding RNAs as biomarkers for acute myocardial infarction.非编码 RNA 作为急性心肌梗死的生物标志物。
Acta Pharmacol Sin. 2018 Jul;39(7):1110-1119. doi: 10.1038/aps.2017.205. Epub 2018 Apr 26.
10
Small RNAs in Rat Sperm Are a Predictive and Sensitive Biomarker of Exposure to the Testicular Toxicant Ethylene Glycol Monomethyl Ether.大鼠精子中的小分子 RNA 是接触睾丸毒性物质乙二醇单甲醚的预测性和敏感生物标志物。
Toxicol Sci. 2019 Jun 1;169(2):399-408. doi: 10.1093/toxsci/kfz041.

引用本文的文献

1
Genetic and epigenetic landscape of male infertility.男性不育的遗传和表观遗传格局
Trends Genet. 2025 Aug 21. doi: 10.1016/j.tig.2025.07.007.
2
Improving sperm selection strategies for assisted reproduction through closing the knowledge gap in sperm maturation mechanics.通过弥合精子成熟机制方面的知识差距来改进辅助生殖中的精子筛选策略。
Hum Reprod Open. 2025 Jul 3;2025(3):hoaf040. doi: 10.1093/hropen/hoaf040. eCollection 2025.
3
Small RNA in sperm-Paternal contributions to human embryo development.精子中的小RNA——父方对人类胚胎发育的贡献

本文引用的文献

1
International Committee for Monitoring Assisted Reproductive Technology: world report on assisted reproductive technology, 2011.国际辅助生殖技术监测委员会：《2011 年世界辅助生殖技术报告》。
Fertil Steril. 2018 Nov;110(6):1067-1080. doi: 10.1016/j.fertnstert.2018.06.039.
2
tsRNAs: The Swiss Army Knife for Translational Regulation.tsRNAs：翻译调控的瑞士军刀。
Trends Biochem Sci. 2019 Mar;44(3):185-189. doi: 10.1016/j.tibs.2018.09.007. Epub 2018 Oct 5.
3
SPORTS1.0: A Tool for Annotating and Profiling Non-coding RNAs Optimized for rRNA- and tRNA-derived Small RNAs.
Nat Commun. 2025 Jul 17;16(1):6571. doi: 10.1038/s41467-025-62015-2.
4
Redox-Driven Epigenetic Modifications in Sperm: Unraveling Paternal Influences on Embryo Development and Transgenerational Health.精子中氧化还原驱动的表观遗传修饰：揭示父系对胚胎发育和跨代健康的影响
Antioxidants (Basel). 2025 May 9;14(5):570. doi: 10.3390/antiox14050570.
5
Sperm tRNA-derived fragments expression is potentially linked to abstinence-related improvement of sperm quality.精子来源的tRNA片段表达可能与禁欲相关的精子质量改善有关。
Asian J Androl. 2025 Sep 1;27(5):638-645. doi: 10.4103/aja2024123. Epub 2025 Mar 18.
6
Impact of physical activity on semen quality: a review of current evidence.体育活动对精液质量的影响：当前证据综述
Asian J Androl. 2025 Sep 1;27(5):574-580. doi: 10.4103/aja20252. Epub 2025 Mar 14.
7
The composition of human sperm sncRNAome: a cross-country small RNA profiling.人类精子小非编码RNA组的组成：一项跨国小RNA谱分析
Reprod Biol Endocrinol. 2025 Mar 6;23(1):36. doi: 10.1186/s12958-025-01358-3.
8
The Small Non-Coding RNA Profile of Human and Mouse Sperm.人类和小鼠精子的小非编码RNA谱
Noncoding RNA. 2025 Feb 9;11(1):15. doi: 10.3390/ncrna11010015.
9
Genome-Wide microRNA Expression Profiling in Human Spermatozoa and Its Relation to Sperm Quality.人类精子中的全基因组微小RNA表达谱及其与精子质量的关系
Genes (Basel). 2025 Jan 4;16(1):53. doi: 10.3390/genes16010053.
10
CircMYH9/miR-133a-3p/CXCR4 axis: a novel regulatory network in sperm fertilization and embryo development.环状肌球蛋白重链9/微小RNA-133a-3p/趋化因子受体4轴：精子受精和胚胎发育中的新型调控网络
Mol Biomed. 2024 Dec 13;5(1):69. doi: 10.1186/s43556-024-00236-5.
SPORTS1.0：一种针对 rRNA 和 tRNA 衍生的小 RNA 进行注释和分析的非编码 RNA 工具。
Genomics Proteomics Bioinformatics. 2018 Apr;16(2):144-151. doi: 10.1016/j.gpb.2018.04.004. Epub 2018 May 3.
4
Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs.Dnmt2 通过精子小非编码 RNA 介导亲代获得的代谢紊乱的跨代传递。
Nat Cell Biol. 2018 May;20(5):535-540. doi: 10.1038/s41556-018-0087-2. Epub 2018 Apr 25.
5
A sequence of 28S rRNA-derived small RNAs is enriched in mature sperm and various somatic tissues and possibly associates with inflammation.一段源自28S rRNA的小RNA序列在成熟精子和各种体细胞组织中富集，并且可能与炎症相关。
J Mol Cell Biol. 2017 Jun 1;9(3):256-259. doi: 10.1093/jmcb/mjx016.
6
MINTmap: fast and exhaustive profiling of nuclear and mitochondrial tRNA fragments from short RNA-seq data.MINTmap：从短 RNA-seq 数据中快速而全面地分析核和线粒体 tRNA 片段。
Sci Rep. 2017 Feb 21;7:41184. doi: 10.1038/srep41184.
7
Epigenetic inheritance of acquired traits through sperm RNAs and sperm RNA modifications.通过精子RNA和精子RNA修饰实现获得性性状的表观遗传继承。
Nat Rev Genet. 2016 Dec;17(12):733-743. doi: 10.1038/nrg.2016.106. Epub 2016 Oct 3.
8
Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals.哺乳动物精子成熟和受精过程中tRNA片段的生物发生及功能
Science. 2016 Jan 22;351(6271):391-396. doi: 10.1126/science.aad6780. Epub 2015 Dec 31.
9
Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder.精子 tsRNAs 导致获得性代谢紊乱的跨代遗传。
Science. 2016 Jan 22;351(6271):397-400. doi: 10.1126/science.aad7977. Epub 2015 Dec 31.
10
The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting.《伊斯坦布尔胚胎评估共识工作坊：专家会议记录》。
Hum Reprod. 2011 Jun;26(6):1270-83. doi: 10.1093/humrep/der037. Epub 2011 Apr 18.