Stupfel M, Gourlet V, Court L, Demaria Pesce V H
Physiol Behav. 1986;38(2):265-74. doi: 10.1016/0031-9384(86)90162-9.
Twenty adult male SPF Sprague-Dawley rats, grouped by 5 and synchronized by a light (L)-dark (D) 12:12 alternation, were deprived of food and water for 7 days; 20 other rats were taken as controls. Continuous measurement of emitted carbon dioxide (VCO2), which was taken as an index of respiratory and metabolic exchanges, shows that starvation significantly (p less than 0.001) decreases the amplitudes of the circadian VCO2 rhythms (by 42.5% during L and 35.6% during D) and also the L----D photic VCO2 responses (by 9.2%; p less than 0.05). Concerning ultradian rhythms of mean and great periods (40 min less than tau less than 24 hr), food and water suppression diminishes their amplitudes (by 58.4% in L and 32.4% in D) and changes their phases (by a 1.29 radian advance in L and a 0.68 radian delay in D). Rats recovered their prestarvation circadian and ultradian VCO2 rhythms 6-7 days after food and water had been given back to them.
将20只成年雄性无特定病原体（SPF）的斯普拉格-道利大鼠按每组5只进行分组，并通过12小时光照（L）-12小时黑暗（D）交替进行同步处理，使其禁食禁水7天；另外20只大鼠作为对照。连续测量呼出的二氧化碳（VCO2），将其作为呼吸和代谢交换的指标，结果显示饥饿显著（p<0.001）降低了昼夜VCO2节律的振幅（光照期间降低42.5%，黑暗期间降低35.6%），同时也降低了光照-黑暗光刺激下的VCO2反应（降低9.2%；p<0.05）。关于平均周期和大周期（40分钟<τ<24小时）的超日节律，食物和水的限制降低了它们的振幅（光照期间降低58.4%，黑暗期间降低32.4%）并改变了它们的相位（光照期间提前1.29弧度，黑暗期间延迟0.68弧度）。在恢复给予食物和水6-7天后，大鼠恢复了饥饿前的昼夜和超日VCO2节律。
