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与马矫形内固定相关的手术部位感染:155例(2008 - 2016年)

Surgical site infection associated with equine orthopedic internal fixation: 155 cases (2008-2016).

作者信息

Curtiss Alexandra L, Stefanovski Darko, Richardson Dean W

机构信息

Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania.

出版信息

Vet Surg. 2019 Jul;48(5):685-693. doi: 10.1111/vsu.13216. Epub 2019 Apr 16.

Abstract

OBJECTIVE

To determine the prevalence of surgical site infection (SSI) after internal fixation and to identify risk factors for SSI and nonsurvival.

STUDY DESIGN

Retrospective study.

ANIMALS

One hundred fifty-five horses with long bone fractures or arthrodesis treated by internal fixation at 1 hospital between 2008-2016.

METHODS

Signalment, diagnosis, surgical repair, surgeon, surgical time, antimicrobial use, SSI onset, bacterial identification, and adjunct treatments were recorded. Perioperative variables were analyzed to identify risk factors associated with outcomes.

RESULTS

Surgical-site infection was reported in 22 of 155 (14.2%) horses, which is lower than what has been previously reported (P = .003). Horses with fetlock arthrodesis or ulnar fracture were more likely to develop SSI. Local prophylactic antimicrobial therapy was associated with an increased risk of SSI. Horses with SSI were 12 times (P < .0001) less likely to survive to discharge than horses without SSI. Horses with a fetlock or carpal arthrodesis or those with radial/humeral/femoral fractures were less likely to survive. No association was identified between open fractures, open reduction and internal fixation, or surgical times and SSI.

CONCLUSION

The prevalence of SSI in this population was lower than what has been previously reported. Horses with fetlock or carpal arthrodesis or radial/humeral/femoral fractures were at increased risk for SSI and/or nonsurvival to discharge. A protective role of local antimicrobial therapy for SSI could not be established.

CLINICAL RELEVANCE

The impact of SSI on outcomes of cases of equine internal fixation remains substantial. Identification of cases at higher risk of SSI should influence surgical technique, postoperative management, and early intervention when SSI is suspected. Additional investigation is warranted regarding local antimicrobial therapy.

摘要

目的

确定内固定术后手术部位感染(SSI)的发生率,并识别SSI和非存活的危险因素。

研究设计

回顾性研究。

动物

2008年至2016年间在1家医院接受内固定治疗的155匹长骨骨折或关节固定术的马。

方法

记录动物的特征、诊断、手术修复、外科医生、手术时间、抗菌药物使用、SSI发病情况、细菌鉴定和辅助治疗。分析围手术期变量以识别与预后相关的危险因素。

结果

155匹马中有22匹(14.2%)报告发生手术部位感染,低于先前报道的发生率(P = 0.003)。跗关节固定术或尺骨骨折的马发生SSI的可能性更高。局部预防性抗菌治疗与SSI风险增加相关。发生SSI的马存活至出院的可能性比未发生SSI的马低12倍(P < 0.0001)。跗关节或腕关节固定术的马或桡骨/肱骨/股骨骨折的马存活的可能性较小。开放性骨折、切开复位内固定或手术时间与SSI之间未发现关联。

结论

该群体中SSI的发生率低于先前报道。跗关节或腕关节固定术或桡骨/肱骨/股骨骨折的马发生SSI和/或非存活至出院的风险增加。无法确定局部抗菌治疗对SSI的保护作用。

临床相关性

SSI对马内固定病例预后的影响仍然很大。识别SSI风险较高的病例应影响手术技术、术后管理以及怀疑发生SSI时的早期干预。有必要对局部抗菌治疗进行进一步研究。

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