a The Parker Institute, Copenhagen University Hospital Fredriksberg , Copenhagen , Denmark.
b The Swedish Knee Arthroplasty Register , Lund , Sweden.
Acta Orthop. 2019 Aug;90(4):360-365. doi: 10.1080/17453674.2019.1604940. Epub 2019 Apr 17.
Background and purpose - Patient-reported outcome (PRO) in total knee arthroplasty (TKA) patients with high body mass index (BMI) is controversial. We compared pain, function, quality of life, general health, and satisfaction among different BMI categories preoperatively and 1 year after primary TKA. Patients and methods - 4,318 patients were operated with a TKA for knee osteoarthritis in the Region of Skane in 2013-2015. In all, 3,327 patients (77%) had complete PRO data and information on BMI and were included. Preoperatively the patients filled in the Knee injury and Osteoarthritis Outcome Score (KOOS) and EQ-VAS (general health). 1 year postoperatively the same questionnaires were filled in together with a question asking whether they were satisfied with the surgery. Information on age, sex, BMI, and ASA grade were obtained from the Swedish Knee Arthroplasty Register. Each patient was classified as Outcome Measures in Rheumatology- Osteoarthritis Research Society International (OMERACT-OARSI) responder or not based on a combination of absolute and relative changes in scores. Welch's t-test and a chi-square test were used in the statistical analysis. Results - Both preoperatively and 1 year postoperatively the obese patients reported somewhat worse scores than the normal weight and overweight. The differences were small with 1 exception, the KOOS sport- and recreation function postoperatively, where normal-weight and overweight patients reported fewer problems than obese patients with a BMI over 35 (40 and 39 points vs. 31 points, p < 0.001). Similar proportions of patients were satisfied and categorized as OMERACT-OARSI responders in the different BMI categories. Interpretation - The degree of improvement in PROs 1 year after TKA surgery does not seem to be affected by BMI.
背景与目的 - 对于体重指数(BMI)较高的全膝关节置换术(TKA)患者,患者报告的结果(PRO)存在争议。我们比较了不同 BMI 类别患者的术前和初次 TKA 后 1 年的疼痛、功能、生活质量、总体健康状况和满意度。
患者与方法 - 2013 年至 2015 年,在斯科讷地区对 4318 例膝关节骨关节炎患者进行了 TKA 手术。共有 3327 例(77%)患者 PRO 数据完整,且具有 BMI 和信息,纳入本研究。术前患者填写膝关节损伤和骨关节炎结果评分(KOOS)和 EQ-VAS(总体健康)。术后 1 年,患者再次填写相同的问卷,并询问他们对手术是否满意。患者的年龄、性别、BMI 和 ASA 分级信息从瑞典膝关节置换登记处获得。根据评分的绝对和相对变化,每位患者被分类为 OMERACT-OARSI 反应者或非反应者。统计分析采用 Welch's t 检验和卡方检验。
结果 - 肥胖患者在术前和术后 1 年均报告了稍差的评分,而非肥胖和超重患者。只有 1 个例外,即术后 KOOS 运动和娱乐功能,超重和肥胖患者(BMI 超过 35)的报告问题较少,而正常体重和超重患者的报告问题较少(40 和 39 分比 31 分,p < 0.001)。在不同 BMI 类别中,有相似比例的患者对手术满意并被归类为 OMERACT-OARSI 反应者。
解释 - TKA 手术后 1 年 PRO 的改善程度似乎不受 BMI 的影响。