From the Department of Epidemiology, Rollins School of Public Health, Emory University; Atlanta, GA.
Sex Transm Dis. 2019 Jul;46(7):465-473. doi: 10.1097/OLQ.0000000000001008.
Human papillomavirus (HPV) and HPV-associated cancer rates are high among men who have sex with men (MSM). The US Advisory Committee on Immunization Practices recommends HPV vaccination for all MSM through age 26 years. We examined trends in HPV vaccine uptake among young US MSM between 2014 and 2017.
Cochran-Armitage tests and estimated annual percentage changes were used to examine annual trends (2014-2017) in HPV vaccination initiation among US MSM ≤26 years as of 2011 who participated in a nationwide annual cross-sectional online survey. We identified independent correlates of HPV vaccination in 2017 using Poisson regression modeling.
There were 2,381 participants in 2014; 4,143 in 2015; 3,926 in 2016; and 3,407 in 2017. Mean age was 23.5 years, 39% lived in metropolitan areas, and 37% lived in the South. HPV vaccination significantly increased (P < 0.0001) from 22.5% in 2014 to 37.6% in 2017 (estimated annual percentage change = 17.4%). HPV vaccination was significantly greater for MSM who were younger, had health insurance, saw a healthcare provider in the past 12-months, resided in the Northeast, resided in metropolitan areas, had higher household income, disclosed their sexual identity to health care provider, and had gonorrhea/chlamydia diagnosis in the past 12-months.
Human papillomavirus vaccination among MSM increased from 2014 to 2017, but vaccine uptake varied significantly by MSM subgroup. Despite favorable trends, the HPV vaccination coverage for this population (37.6%) is less than half of the Healthy People 2020 target (80%). Additional efforts are needed to increase coverage.
男男性行为者（MSM）的人乳头瘤病毒（HPV）感染率和 HPV 相关癌症发病率较高。美国免疫实施咨询委员会建议，所有 MSM 都应在 26 岁之前接种 HPV 疫苗。我们研究了 2014 年至 2017 年期间美国年轻 MSM 中 HPV 疫苗接种率的趋势。
采用 Cochran-Armitage 检验和估计年度百分比变化来检测 2011 年≤26 岁的美国 MSM 中 HPV 疫苗接种起始的年度趋势（2014-2017 年），他们参加了一项全国性的年度横断面在线调查。我们使用泊松回归模型确定了 2017 年 HPV 疫苗接种的独立相关因素。
2014 年有 2381 名参与者；2015 年有 4143 名参与者；2016 年有 3926 名参与者；2017 年有 3407 名参与者。平均年龄为 23.5 岁，39%居住在大都市区，37%居住在南部。HPV 疫苗接种率从 2014 年的 22.5%显著增加到 2017 年的 37.6%（估计年度百分比变化为 17.4%）（P < 0.0001）。在年龄较小、有医疗保险、在过去 12 个月内看过医疗保健提供者、居住在东北部、居住在大都市区、家庭收入较高、向医疗保健提供者披露过性取向、在过去 12 个月内诊断出淋病/衣原体感染的 MSM 中，HPV 疫苗接种率显著更高。
从 2014 年到 2017 年，MSM 中的 HPV 疫苗接种率有所增加，但 MSM 亚组之间的疫苗接种率差异显著。尽管呈上升趋势，但该人群的 HPV 疫苗接种率（37.6%）仍不到 2020 年“健康人”目标（80%）的一半。需要进一步努力来提高覆盖率。
